Three cases of pulmonary fibrous histiocytoma, sometimes known as xanthogranuloma and fibrous xanthoma, are described. The lesion is part of a spectrum of diseases known as postinflammatory pseudotumors of the lung. It is usually discovered on routine radiographic examination on which it appears as a well circumscribed mass, and it usually has a benign course. The microscopic findings upon which diagnosis is based, the theories of origin, and previously reported cases are discussed.
Pulmonary hemorrhage is generally due to neoplasm, tuberculosis, necrotizing pneumonia, or bronchiectasis. If these are not found, kidney diseases, including anti-glomerular basement membrane antibody-induced bleeding (Goodpasture's syndrome), should be considered. Hemoptysis in renal disease is more often due to azotemic hypervolemia than immune reaction. Typically linear immunofluorescent patterns along the glomerular and pulmonary alveolar basement membranes must be demonstrated to confirm the diagnosis of Goodpasture's syndrome.
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