The preparation and properties are described for alternate members of a homologous and of an isomeric series of purified sodium salts of secondary alcohol sulfates, containing from 11 to 19 carbon atoms, and for a straight hydrocarbon chain with the sulfate group in various positions. The purified sodium salts of the primary alcohol sulfates with 10, 12, 14, and 16 carbon atoms are also examined.Measurements have been made of the surface tension and foaming, wetting, and detersive properties of solutions of these compounds in water and with added electrolytes. Solubilities of sodium salts of the secondary and primary alcohol sulfates studied are reported at 50 intervals from 20°to 4(j°C. The data are discussed from the point of view of correlating changes in the properties involving surface activity when the structure and molecular weight of the compound are changed.

The alkyl esters of p-aminobenzoic acid, because of their insolubility in water, cannot be employed for anesthetic purposes in aqueous solution, and the corresponding salts, though soluble, are far too acid in character to be used. The bases have, therefore, found their chief application as dusting powders. Numerous attempts have been made to correlate chemical constitution and physiological action of members of this series but there seems to be very little agreement among different investigators even where similar methods of testing were used; moreover, each previous worker has dealt with only a few members of the series. No attempt has been made to correlate physical properties and physiological action of these compounds.This investigation involved the preparation and study of various alkyl ^-aminobenzoates, namely, methyl, ethyl, propyl, isopropyl, n-, iso-, sec.-and tert.-butyl, «-amyl and allyl. The relative physiological action of these anesthetics on goldfish, the surface tension effects and the partition coefficients between amyl acetate and water have been determined and compared.Physiological Action.-Sturmer and Luders1 tested a few of these anesthetics on the mucous membrane of the mouth and found that the npropyl ester was strong, isopropyl weaker, isobutyl weaker and that the isoamyl was strong but irritating. They concluded that increase in molecular weight of the alcohol results in decrease of anesthetic value and increase in toxicity.

effect of the peptide linkage on dissociation, are briefly discussed. and other questions relating to these compounds, Boston, Mass.

n ‐Hexyl alcohol product: n ‐Hexyl alcohol

No abstract