SummaryA benchtop SFCIMS system is described which utilizes supercritical carbon dioxide in a 50 micron diameter open tubular column interfaced directly to an unchanged commercially available benchtop capillary GCIMS system equipped with a chemical ionization (Cl) source. A small amount of methane reagent gas was admitted co-axially to a capillary restrictor at the exit of the capillary chromatographic column. This make-up gas served as the CI reagent gas and appeared to optimize the sensitivityof thesystem while providing abundant (M+l) ionsfor the analytes investigated in this study. Good chromatographic integrity was obtained for the GCIMS test compound, decafluorotriphenylphosphine (DFTPP), but the capillary restrictor appeared to cause some tailing of the ion current profiles resulting from low nanogram levels of caffeine and some fatty acid esters. Improvements in the SFCIMS capillary restrictor interface and the pumping system of the benchtop GCIMS system should increase the capability of this system for future applications.
Volatile organic compounds (VOCs) provide insight into the taste and aroma of milk. VOCs in milk are typically analyzed using headspace gas chromatography–mass spectrometry (GC‐MS). While static headspace GC‐MS is a simple and widely applicable analytical technique for the analysis of VOCs in various samples, it has not been frequently applied to milk samples. In this study, static headspace GC‐MS was used to compare the VOCs of three different brands of commercial milk. Three components were identified in the samples, that is, acetone, toluene, and 2‐heptanone, where the concentration ranges of acetone, toluene, and 2‐heptanone in the milk samples were 2.284–3.256, 0.028–0.178, and 0.014–0.020 μg/mL, respectively. A literature review found that all three components were previously reported in milk, while toluene and 2‐heptanone were newly identified using headspace GC‐MS in this study.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.