Chronically implanted electrodes allowed the repeated stimulation, with different rates and intensities and for variable durations, of the paleocerebellum in 4 patients with intractable muscular hypertonia and also in a patient with epilepsy resistant to antiepileptic drugs. Chronic stimulation of the anterior cerebellum at high rates (100–200 cycles per second) inhibited muscular hypertonus. Chronic stimulation at 10 cycles per second in the patient with epilepsy inhibited the seizures.

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