Aim To compare the performance of Heidelberg retina tomograph (HRT) and scanning laser polarimetry (GDx) with photographic evaluation of the optic nerve head (ONH) and retinal nerve fiber layer (RNFL) in the application of the Finnish Evidence-Based Guideline for Open-Angle Glaucoma. Methods A total of 41 control participants and 312 patients referred for glaucoma evaluation were included in the study. All the participants underwent ophthalmic evaluation, ONH stereophotography, monochromatic RNFL photography, HRT, optical coherence tomography, and GDx evaluation. Participants were classified on the basis of stereophotographic or imaging device results based by applying the Finnish Guideline.Results Agreement between the stereophotographic evaluation and that on the basis of the imaging devices was 52.9%. Classification of patients with similar management advice on the basis of these evaluations had 56.4% agreement. The specificity of the Finnish guideline for detecting normal patients was 78% (stereophotography) and 83% (imaging devices). Optic disc size interfered with the diagnosis in patients evaluated using the HRT3 glaucoma probability score. Structural changes were more frequently detected before functional changes. Conclusion The Finnish Evidence-Based Guideline for Open-Angle Glaucoma is useful for classifying normal participants and patients with suspected glaucoma or glaucoma through either conventional stereophotographic evaluation of the neuroretinal structures or with the new imaging devices.
Metastatic tumors are the most common intraocular malignancies, and the choroid is by far the most frequent location for the intraocular metastases. Metastases from a laryngeal carcinoma are quite unusual. Lesions affecting both choroid and optic nerve are extremely rare.
Purpose Evaluate the effect of extreme central corneal thickness in RNFL parameters measured by GDx VCC.
Methods A total of 131 eyes of 131 subjects were included divided into 60 control and 71 glaucoma patients. All of the glaucoma eyes had reproducible defects on standard automated perimetry. Central corneal thickness was measured with an ultrasonic pachymeter. ROC curves were plotted in the sample subgroups with exteme pachimetry values (outside mean ± 2SD) and were compared with ROC curves of the subjects in the normal pachimetry range (mean ± 2SD).
Results No differences were found in the areas under the ROC curve of the parameter of the GDx VCC in thinnest and thickest subgroups when compared with the mean pachymetry group.
Conclusion Central corneal thickness has no influence in RNFL measurements of GDx VCC.
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