The article presents the study that mainly focused on the changes made as a result of collaborative innovations in business relationships developed during the period of digitalisation in the construction field of the Russian Federation. It is a conceptual piece of work based on the systematic approach to the analysis, literature review and comparative analysis. The digitalisation of investment and construction projects is technologically based on the integration of solutions, such as the building information model (BIM), high-performance IT-systems, cloud platforms and the Internet-of-Things, resulting in unified and constant connectivity, specialised mobile applications, robotic equipment, unmanned vehicles, additive technologies, AR/VR services for the analysis of Big-Data, and blockchain technologies. The integration of digital technologies is a radical innovation, which highlights collaborative innovations in business relationships and makes it possible to form a united digital ecosystem that allows firms to manage, control and regulate the full lifecycle of a construction project, and then, the property in real-time. The contribution of this work to the construction field is the offered model for the creation of a digital ecosystem and the described role of the government in the model. Also, this work can be used for the integration of BIM technologies in construction companies.
The objective of this article is conducting the analysis of economic growth, being a key factor in the dynamics of level and quality of life of the population, as well as to develop the related suggestions, in order to accelerate and stabilize such processes in Ukraine. This research presents the analysis of the real GDP’s changing rate in recent years, along with the assessment of another evidence of the economic growth i.e. the income of the population. The related crosscountry comparative analysis of the level of population’s well-being has been performed. The reasons for Ukraine’s significant lagging behind its neighboring regions and other European countries in terms of main economic indicators have been determined. We’ve defined the “poverty trap”, the authors believe that it is the current state of Ukrainian Economy. The related suggestions aimed to accelerate and stabilize the economic growth in Ukraine have been developed.
Studying of the prevalence of CHF in patients with arterial hypertension and ischemic heart disease, and of the specifity of CHF in patients of different sex and age. Retrospective analysis of CHF prevalence in 2048 patients, prospective study of different types of CHF in 285 patients with conduction of echocardiography and 6 min walk test. The prevalence of CHF in our group was 29 %, in men it was found 2.8 times more often than in women. 71 % of patients with CHF were older than 60 years. Significant differences were revealed in etiology of CHF in men and women, and in patients of different age. CHF with E < 45 % was diagnosed in 35.8 % of patients, men had this type of CHF 5.8 times more often than women. CHF with preserved EF was in 64.2 % of patients, the amount of women with this variant of CHF increases to 33.3 %. Purposeful examination of patients with arterial hypertension and IHD is needed for early detection of CHF.
Цель. Оценить эффективность применения унифицированного опросника для выявления различных форм цереброваскулярных заболеваний (ЦВЗ) у боль-ных артериальной гипертонией (АГ) среднего возраста, находящихся под наблюдением участкового терапевта. Материал и методы. Обследованы 257 чел. с АГ 1-3 степени, пришедших на прием к врачу-терапевту "по любому поводу". Проводился опрос с приме-нением унифицированного опросника, включающего вопросы для выявления вероятности острых форм ЦВЗ в анамнезе и хронических форм на момент обследования, вопросы для выявления болей в грудной клетке при напряже-нии и перемежающейся хромоты, выполнялась регистрация электрокардио-граммы (ЭКГ) с оценкой по Миннесотскому коду. Верификация диагноза осу-ществлялась независимыми врачами-специалистами -неврологом и кардио-логом, назначавшими при необходимости дополнительные методы обследования. Результаты. Различные формы ЦВЗ диагностированы у 148 (57,6%) больных АГ, в том числе острые формы в анамнезе -у 21 (8,2%) чел., хронические формы на момент обследования -у 53 (20,6%) чел., острые в сочетании с хроническими формами -у 74 (28,8%) чел. Ранее не диагностированные ЦВЗ определены у 20,2% больных. Гипертонический церебральный криз (ГЦК) до начала исследования имелся в амбулаторной карте у 4 (1,6%) чел., в 72 (28,0%) случаях данный диагноз был установлен впервые с помощью унифи-цированного опросника. Заключение. Применение унифицированного опросника у больных АГ повы-шает выявляемость начальных форм хронической цереброваскулярной пато-логии и ГЦК, перспективных с точки зрения профилактики развития инсульта. Опросник может быть использован в условиях поликлиники, в частности при диспансеризации взрослого населения. Aim. To assess the effectiveness of the use of a unified questionnaire for various cerebrovascular diseases types screening (CVD) in patients with arterial hypertension (AH) of middle age that are under general physician observation. Material and methods. Totally 257 pts. screened with AH 1-3 grade, admitted general physician "by any complaint". The survey performed with a unified questionnaire that includes questions for the chance of acute CVD types onset in anamnesis and chronic types at the moment of screening, questions on the chest pain assessment with exertion, and intermittent claudication, ECg registered with Minnesota coding. Diagnosis verification was done by independent physiciansneurologist and cardiologist, who ordered additional investigation methods.Results. Various CVD types were diagnosed in 148 (57,6%) patients with AH, including acute types in anamnesis -in 21 (8,2%), chronic at the moment of study -in 53 (20,6%), acute and chronic -in 74 (28,8%). Previously nondiagnosed types found in 20,2% of patients. Hypertensive cerebral crisis (HCC) before the beginning of study was mentioned in the patient's chart in 4 (1,6%) patients, in 72 (28,0%) cases this diagnosis was set first time with the unified questionnaire.Conclusion. The usage of unified questionnaire in AH patients increases the rate of finding of chronic cerebro...
Objectives The aim of the study was to assess the levels of the antibody to C1q complement component (anti-C1q) in the sera of patients (pts) with lupus nephritis (LN) in relation to the clinical activity of SLE during anti-B-cell therapy with Rituximab (RTM). Methods The study involved 41 pts with definiteSLE (3 male, 38 female; mean age Me 27,5[22-36]).The concentration of anti-C1q in the blood were determined by immunoenzyme methods. Associations between levels of anti-C1q antibodies and parameters of LN were statistically analyzed. Patients were divided into 2 groups: those with LN (n=25) and without renal involvement (n=16).Marked highly positive (>30U/ml), low positive (10-30U/ml) and negative (≤10U/ml) levels of anti-C1q. Results In pts with LN highly positive levels of anti-C1q occurred significantly more frequently than in pts without renal involvement (p=0.04). The majority of pts without LN had negative and low positive levels anti-C1q. In the group of 25 pts with nephritis in 7 were highly positive levels of anti-C1q, and in the rest of pts were found negative and low positive levels of anti-C1q. In pts without nephritis (n=16) in only one was detected highly positive anti-C1q. In patients with nephritis in a month after treatment with RTM was observed a significant decrease of levels of anti-C1q (p=0.002), which persisted through a year after treatment with RTM (p=0.006). There was no association between SLE activity index SLEDAI 2K and the level of anti-C1q before initiating therapy. Conclusions The results of recent studies suggest that there is a link between the presence of highly positive levels of anti-C1q Abs and kidney involvement in SLE. As a result of therapy with RTM revealed a significant decrease of levels of anti-C1q Abs. Disclosure of Interest None Declared
The goal of research is to develop recommendations for improving the mechanism of income taxation in Russia, taking into account the best foreign practices.The framework of studies was the monographic method and the method of comparative analysis of statistics and legislative documents of the financial authorities of Russia and leading foreign countries, as well as methods of modeling and generalization of the results.The necessity of strengthening the social function of income taxation is substantiated. A comparative analysis of modern taxation of personal income in Russia and abroad is carried out. As a result of the research, it was revealed that the main share of this tax is provided by taxing the incomes of the poorest segments of the population, which contradicts the principles of fair taxation.To improve the mechanism of taxation of incomes of Russian citizens, the experience of leading foreign countries in the application of a progressive scale, family taxation, the establishment of a tax-free minimum (allowance) and tax deductions was used. Particular attention is paid to introducing a tax-free minimum into the mechanism for applying standard deductions taking into account the cost of living.
The article presents an overview of the concept of tax literacy as the main element of financial literacy and the necessary prerequisite for the formation of the tax culture of society and the individual. The expansion of the field of knowledge and skills that form the tax literacy of the population in the era of the digital economy is shown.The aim of the study is to analyze the prerequisites for the formation and development of tax literacy in the Russian Federation and its impact on improving the efficiency of the tax system. The study used traditional methods of scientific research, the monographic method, and the method of comparative analysis.The results of a comparative analysis of the level of financial literacy in different countries showed the insufficiency of its development in Russia. Based on the analysis of the state of taxation of individuals in the Russian Federation, the problems of the formation of tax literacy and tax culture of the population of Russia are identified, for the solution of which the author formulated proposals.
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