The Timed 25 Foot Walk (T25FW), a test of maximum walking speed on a short distance, is commonly used to monitor ambulation status and to assess treatment outcomes in MS. The main goal of this study was to determine how walking speed on the T25FW correlates with other clinician-reported and patient-reported measures in an outpatient MS rehabilitation clinic. We analyzed cross-sectional data systematically collected during a physiatry evaluation for the management of spasticity and walking limitations. In addition to demographic variables and the Expanded Disability Status Scale (EDSS), measures of body functions [lower extremity manual muscle testing (LE MMT), lower extremity Modified Ashworth Scale (LE MAS), Fatigue Severity Scale (FSS), leg pain], and measures of activity and quality of life [reported frequency of falls, Incapacity Status Scale (ISS), Rivermead Mobility Index (RMI), EQ-5D health questionnaire, and Patient Health Questionnaire-9 items (PHQ-9)] were administered. A multivariate regression analysis was conducted. 199 patients were included in the analysis (age 49.41(9.89) years, disease duration 15.40 (10.22) years, EDSS score 5.6 (1.2), and T25FW speed 70.93(44.13) cm/s). Both EDSS and LE MMT were significantly correlated with T25FW speed (R square 0.692, p<0.001). After adjusting for EDSS and LE MMT, lower T25FW speed was associated with higher ISS scores (R square=0.316, p<0.001), lower RMI scores (R square=0.540, p<0.001), and higher frequency of falls. EQ-5D and PHQ-9 were not significantly associated with T25FW speed. Our findings support the clinical relevance of the T25FW in the rehabilitation of patients with MS.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.