Background: Psoriasis is a chronic immune-inflammatory-mediated disease in which its pathogenesis involves an interaction between genetic, environmental, and immunological factors and is characterized by topical skin lesions as well as an increased risk for cardiovascular disease. There is increasing evidence that patients with psoriasis are more associated with cardiovascular disease as compared with the general population. The aim was to assess the cardiac performance in patients with psoriasis and compare with control participants and compare between conventional two dimensional echocardiography and global longitudinal strain changes.Methods: A case control study of 57 psoriasis patients and 57 control participants who attend the Dermatology unit in Marjan medical city between the first of March and the first of June of 2019, were recruited in study. The patients who met the inclusion criteria, invited to do echocardiogram. In echocardiography unit, the participant's age, duration of disease and sex was recorded and echocardiography done using conventional and 2 dimension STE. Student T tests and ANOVA test were used to found the mean difference in echocardiograph measurement between patients and control participants.Results: There were a no significant difference in conventional parameter between the psoriasis patients and the controls. There was a statistically significant difference in Global longitudinal strainbetween the psoriasis patients and the controls. Global longitudinal strain is decreased by prolong or increase disease duration. Conclusions:The speckle tracking echocardiography techniques was useful noninvasive, reliable and non-expensive tool for detection of subtle myocardial deformation in patients with psoriasis.
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