Objective: To analyze antibacterial activity of essential oil extracted from Curcuma xanthorrhiza Roxb. rhizomes against bacteria causing pulp necrosis, Enterococcus faecalis, and Fusobacterium nucleatum. Material and Methods: The method used in this research was discdiffusion on MH-A media, based on the standard protocol of National Committee for Clinical Laboratory Standards (NCCLS). This method used 4 replications in each of the study group. The study group consists of 4 different concentration groups (25%, 50%, 75% and 100%) of Temulawak rhizomes essential oil extracts, ChKM and Cresophene were used as the positive control group and DMSO (10%) and Tween 80 (0.5%) was used as the negative control group. Results: The inhibition zones of 25%, 50%, 75%, and 100% of temulawak rhizomes essential oil extracts against E. faecalis were 8.17 mm, 8.54 mm, 9.53 mm and 10.17 mm, respectively. Whereas, the inhibition zones of 25%, 50%, 75% and 100% of temulawak rhizomes essential oil extracts against F. nucleatum were 8.54 mm, 8.95 mm, 9.65 mm and 10.75 mm, respectively. Data analysis using Kruskal-Wallis in both of bacteria showed p=0.00 (p<0.05) and therefore, significant levels of inhibition. Conclusion: Essential oil extracts from C. xanthorrhiza Roxb. rhizomes has medium antibacterial activity against E. faecalis and F. nucleatum.
The mechanical force of orthodontics produces areas of pressure and pull. In the pressure area occurs resorption of alveolar bones carried out by osteoclast cells. The study aims to find out the change in the number of osteoclast cells in the alveolar bone pressure area of mouse teeth that induced mechanical force orthodontics. 36 male rats are divided into 6 groups. Group K: mice are not given a mechanical style of orthodontics. Group P: mechanically styled orthodontics (GMOs). GMOs in mice were administered to the upper jaw molar-1 (M-1) teeth (RA) right and in both RA incisive teeth using Ni-Ti Orthodontic Closed Coil Spring diameter 0.01 inches in orthodontic force of 3.5 oz = 85.05 gr/cm2 = 10 grF for 1 week, 2 weeks and 3 weeks. The results of the study were 1 week (1.99), 2 weeks (1.92), and 3 weeks (1.75). Conclusion of mechanical administration of orthodontic force increases the number of osteoclast cells on the 8th day (1 week), the 15th (2 weeks), and the 22nd (3 weeks). Based on the observation time there was a decrease in the number of osteoclast cells from 1 week to 2 weeks then to 3 weeks but not significant.
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