Percutaneous transluminal angioplasty with stenting of the complete total occlusion of the SA is a safe and effective procedure associated with low risks and good long-term results.
Breast arterial calcifications (BACs) are common findings on mammography which are associated with an increased risk of the coronary artery disease (CAD). Our aim in the current study was to design measurement instruments of CAD prediction, with or without BACs, and its discriminatory validity in the diagnosis of CAD (expressed by Syntax score) in women. This was observational, prospective study in the women cohort which underwent mammography and angiography. In this study, we have demonstrated that the total 'Breast Arterial Calcification and Coronary Artery Disease Scale' was good additional diagnostic tool for detection of patients with severe CAD.
Background/Aim. Patients with acute coronary syndrome (ACS) and diabetes mellitus (DM) have an increased risk of major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI), which is not estimated sufficiently-multidimensionally in terms of type and severity of the ACS and/or DM and angiographic findings. The study was intended to validate and develop an index of metabolic, angiographic, anatomic and clinical risk factors for one-year MACE after conducted PCI in patients with ACS and DM. Methods. A prospective cross-section study was performed in patients with DM and ACS. In the PCI period the following risk factors where were recorded: 1) age and metabolic variablesglycosylated hemoglobin (HbA1c), total cholesterol, triglyceridemia; 2) endocrinological variables-DM therapy, tip of DM; 3) ACS modality; 4) radiological / anatomical variable-SYNTAX score and 5) clinical variables in modified ACEF score. One-year MACE were recorded. Results. From a total of 136 consecutive patients, 55 of them developed at least one MACE in one-year followup. A high predictive risk index was evaluated that assessed particularly or associated risks for one-year MACE (c statistic = 0.879) in the study population, defined by: SYNTAX score > 21, modified ACEF score > 1.38, HbA1c ≥ 8 (%), triglyceridemia ≥ 2.3 (mmol/L) in patients with insulin therapy, and ACS modalityunstable angina pectoris. The constructed Risk Index for one-year MACE (MACERI) has better predictive characteristics than SYNTAX score (c statistic = 0.798), as well as ACF score (c statistic = 0.744). Conclusions. MACERI can potentially have great application in future risk factors studies for one-year MACE in patients with DM and ACS who underwent PCI, because with it the effects of these factors measure multidimensionally at valid and accurate manner.
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