Background:Unlike the western world, Macular Corneal Dystrophy (MCD) is the most common corneal stromal dystrophy in India. It is caused by mutations in the carbohydrate sulfotransferase 6 (CHST6) gene. So far, there are limited numbers of reports on CHST6 screening. Therefore, our screening of CHST6 gene in Indian families with MCD will be useful for genetic diagnosis, carrier detection and genetic counseling to families included in this study and other families with similar disease condition.

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