Background: In normal vascular tissue physiology, calcium plays a crucial role. Calcium and magnesium metabolism have been implicated in the pathogenesis of primary hypertension. The present study aimed to assess serum calcium and serum magnesium levels and to study the association of the serum magnesium and serum calcium levels with hypertension in newly diagnosed hypertensive patients of Bikaner, Rajasthan. Methods: This cross- sectional study was carried out on 60 subjects aged between 18 years to 60 years in the department of physiology and in association with department of medicine and department of cardiology, S. P. Medical College and associated group of hospitals, Bikaner. Data was compiled and entered into Microsoft software statistical package for the social sciences (SPSS) version 22.0. Data was summarised as frequencies, mean and standard deviations. For continuous data the means were compared between cases and controls using unpaired or independent t test; and for nominal data, chi-square or Fisher’s exact tests were applied to compare frequency distribution between cases and controls to see the statistical significance. Results: The present study shows statistically insignificant change in serum calcium and serum magnesium levels in newly detected hypertensive patients when compared to normotensive controls. Conclusions: In view of statistically insignificant change in serum calcium and magnesium levels in newly detected hypertensive patients in our study, further studies with a large sample size and more uniform population are required to find if any significant association exists between these cations and hypertension.
Background: Prescriptions are detailed instructions about a patient’s course of treatment that is provided in writing by a medical professional. Hence, prescription not only manifests the knowledge of medical practitioner but also perspective toward the patient, considering his or her economical and social condition. The study which incorporates components such as availability of drugs, rationality of prescription, cost per prescription, and affordability is called drug utilization study. According to the World Health Organization (WHO), drug utilization is the marketing, distribution, prescribing, and use of medications in society with a focus on the ensuing medical, social, and financial repercussions. To confirm the importance of pharmaceuticals in routine medical practice, it is very helpful and effective to study drug utilization and prescription patterns. These studies have a strong emphasis on many facets of drug use, including prescription, administration, effects, and associated occurrences such as positive or negative drug reactions. Aims and Objectives: This study was aimed to evaluate the prescription pattern of drugs and their utilization in the outdoor patients of dermatology department of a tertiary care hospital in southern Rajasthan. Our objectives were to assess whether the use of drugs is rational or not and to identify different drugs used in various types of dermatological disorders. Materials and Methods: A prospective cross-sectional observation study was conducted over a period of 11 months (May 2020–March 2021) on 400 prescriptions. Patients with severe ailments who were shifted indoor, pregnant women, and patients <18 years were excluded from our study. Data were gathered, recorded, and analyzed using statistics in accordance with a predetermined format. Results: Out of 400 patients included in the study, 64% were males and 36% were female patients. We deduced from this survey that maximum number of patients attending dermatology department were suffering from fungal infection followed by dermatitis. In our study, 508 (41.30%) and 722 (58.69%) of the medicines were delivered topically and orally, respectively. In all patients, topical medications were prescribed to the greatest number of patients. Antihistamines were the medications that were most frequently prescribed in our study, followed by antifungal medications. Tablet levocetirizine is the antihistaminic medicine that is most frequently prescribed, whereas Vitamin E, terbinafine, calcium, and Vitamin D3 are rarely. For a variety of dermatological conditions, the maximum number of patients received three prescription medications. According to the WHO criteria, generic names were prescribed for all of the medications. Conclusion: This drug prescribing and utilization study gives an idea to the prescriber regarding prevalent disease pattern in the area. It also helps to improve quality of prescription and promote rational and cost effective treatment.
INTRODUCTION: Children with parental history of diabetes have inherited susceptibility to develop diabetes. It has been shown that patients with Diabetes Mellitus exhibit altered autonomic activity of cardiovascular system. The present study aimed to determine the early changes in cardiac autonomic modulation by measuring the frequency domain analysis of heart rate variability among healthy subjects with parental history of type 2 diabetes and to compare it with the age and sex matched controls. The study of Cardiovascular Autonomic FunctionsMETHODOLOGY: was carried out in 50 healthy offsprings of Type 2 Diabetic Parents (Case group) and 50 healthy offsprings of Nondiabetic Parents (Control group) in the age range of 18 - 25 years randomly selected among MBBS students of J.L.N. Medical College Ajmer. Statistical Analysis is done by student t-test. Probability P value <0.05 was considered statistically signicant. In offsprings of type 2 diabetic patients signicantly lower HFRESULT: (nu) and signicantly higher LF (Nu) and LF/HF ratio were observed as compared to control group. The present study revealsCONCLUSION: that the Sympathovagal Imbalance (SVI) was due to vagal withdrawal in offspring of type 2 Diabetes Mellitus patients. Impairment in autonomic function is associated with increased risk of future diabetes. Early detection of diabetes can be used for risk stratication at early stages of life and serious consequences can be reduced.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.