Cardiovascular and reproductive health of women have been going hand in hand
since the dawn of time, however, their links have been poorly studied and
once the basis of their connections started to be established in late 20th
century, it depended on local regional abilities and the level of
progressive thinking to afford comprehensive women?s care beyond the ?bikini
medicine?. Further research identified different associations rendering
more conditions sex-specific and launching therefore a slow, yet initial
turn around in clinical trials? concept as the majority of global
cardiovascular guidelines rely on the results of research conducted on a
very modest percentage of women and even less on the women of color.
Currently, the concept of women?s heart centers varies depending on the
local demographics? guided needs, available logistics driven by budgeting
and societal support of a broad-minded thinking environment, free of bias
for everyone: from young adults questioning their gender identity, via women
of reproductive age both struggling to conceive or keep working part time
when healthy and line of work permits it during pregnancy, up to aging and
the elderly. Using ?Investigate-Educate-Advocate-Legislate? as the four
pillars of advancing cardiovascular care of women, we aimed to summarize
standing of women?s health in Serbia, present ongoing projects and propose
actionable solutions for the future.
Baseline insulinaemia, more precisely, fasting hyperinsulinaemia could be a good predictor of significant coronary atherosclerosis in non-diabetic patients, which enables a more elegant cardiometabolic risk assessment in the setting of everyday clinical practice.
Sarcoidosis afflicts the central nervous system more frequently than
previously believed. Neurological symptoms are present in roughly a half of
patients, and depend of the location in central nervous system. The
probability of spontaneous regression is significantly less when compared to
other forms of sarcoidosis, which means that the proper diagnosis and
treatment is paramount. Even when properly treated, functional defects are
not uncommon. Majority of these patients require immunomodulating drugs and
continuous follow-up. New immunomodulating drugs, especially biological
agents, have shown to be significantly more effective, with fewer side
effects, and are important when corticosteroids could not be applied. Less
invasive methods, such as cerebrospinal analysis, help greatly in the
diagnostics procedure, and require further research and improvement
The objective of this study was to evaluate static and dynamic results on the foot pressure measurement and computer simulation for diabetes mellitus patients. The finite element analysis was used to compare with pressure foot measurement. The foot and ankle model consisted of 28 bony segments is created from DICOM CT slice from specific patient with diabetes mellitus diagnosis. All material properties are considered as homogeneous, isotropic and linearly elastic. Foot pressure measurement for both static and dynamic condition gave topographic distribution of high pressure points which is in correlation with clinical tests results. The result for maximum pressure measurement of the left foot 124.74 kPa is in good comparison with finite element results for 121 kPa. It looks that numerical simulation in combination with foot pressure measurement device can be efficient and inexpensive screening tool, which could go in direction for prevention of the diabetic foot complications, associated with high mortality and morbidity that has significant economic impact on healthcare system.
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