Background: Serum albumin is a vital laboratory indicator of nutrition status. Fetal weight depends upon the nutritional status of mothers. Indeed, the serum albumin status at term may help to assume the fetal weight. We do have not enough research-based data regarding this issue. The aim of this study was to estimate maternal serum albumin at term and to observe its correlation with the birth weight of babies. Methods: This cross-sectional analytical study was done at department of gynaecology and obstetrics, Sir Salimullah medical college and Mitford hospital, Dhaka, Bangladesh from July 2019 to June 2020. A total of 96 mother-baby pairs were selected using purposive sampling method. Women with single full-term pregnancy based on fundal height on Naegele’s rule irrespective of any mode of delivery was included in this study. Mothers with normal albumin levels (3.6-5.2 gm/dl) were defined as group A and mothers with low albumin levels (<3.6 gm/dl) in group B. Statistical analyses of the results were obtained by using window-based computer software devised with SPSS-22. Results: In analyzing the maternal serum albumin level, we observed that majority of the participants were with normal albumin levels which were 81% and the rest 19% of patients were low albumin levels. In this study, it was observed that more than half (56.4%) of babies were male in group A and 9 (50.0%) in group B. The majority (94.9%) of babies’ birth weights were ≥2.5 kg in group A and 4 (22.0%) in group B. The difference of birth weight was statistically significant (p<0.05) between the two groups. Maternal serum albumin was significantly associated with birth weight of babies in multivariate analysis. But negatively correlated with newborn birth weight which is statistically significant. Conclusions: Maternal albumin was observed to be directly proportional to the birth weight of babies.
Introduction: Premature rupture of membranes (PROM) is the single most frequent analysis associated with preterm delivery. The major complication of preterm PROM is early delivery. Every year around 28,000 women die due to complications of pregnancy and childbirth in Bangladesh. Nonscientific intervention in PROM made at several stages intensifies the pregnancy complications several times, thereby leading to many more deaths of the foetus and newborn. Methods: A prospective cross-sectional study was carried out in the Department of Obstetrics and Gynae, Dhaka Medical College and Hospital from March 2008 to July 2008.A total of 50 pregnant patients (N=50) with PROM in the maternity unit were enrolled in this study following the inclusive criteria. Data were collected in the pre-designed data collection sheet. Data were analyzed statistical package for social science (SPSS). Result: Commonest organism 72% were no growth, 10% were streptococcus, 6% were E. coli, 2% were delivered alpha-haemolytic streptococcus, 2% were candida, 2% were anaerobes, 2% was chlamydia and 2% pneumococcus. 52% were preterm and 42% were term delivery. 40% were chorioamnionitis, 10% were puerperal sepsis and 8% were DIC. Infection-related, 16% were urinary tract infections, 4% were lower genital traction infections and had no sexually transmitted disease. In fetal outcomes 58% were live birth, 42% were stillbirths, 46% were mature and 54% were premature. 66% were <2.5 kg and 34% were >2.5 kg. Conclusion: Premature rupture of membrane and chorioamnionitis may cause antagonistic maternal consequences linked to infection. Premature rupture of membrane indicated lower birth weight for infants. Proper antibiotics must be certain prophylactically for the anticipation of intra-partum infection in case of PROM.
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