Background: Acne vulgaris is reported as an inflammatory disease of pilosebaceous glands of the skin which mainly occur on the face and trunk. Acne is among one of the most common skin conditions which commonly seen in adolescent’s population. However, it can also present among the adult population. Material & Methods: The present cross‑sectional prospective study 100 patients who were diagnosed with acne vulgaris and 100 controls who were not having acne and without a known clinical disease were enrolled for present study by simple random sampling. Written informed consent was taken from each study participant. Results: SCL 90-R Global Symptom Index was higher and statistically significant ( P value <0.05) among acne group in compared to control group. The mean values of SCL 90-R somatization was higher and statistically significant ( P value <0.05) among acne group in compared to control group. The mean values of Male SCL 90-R depression was higher and statistically significant ( P value <0.05) among acne group in compared to control group. The mean values of Female SCL 90-R anxiety was higher and statistically significant ( P value <0.05) among acne group in compared to control group. Conclusion: We concluded from the present study that acne vulgaris is significantly associated with psychiatric disorders. Patients with acne vulgaris and found that higher prevalence of anxiety and depression among them which was significantly associated with poor quality of life. Key words: Acne, Anxiety, Depression.
Background: Leukoderma is an acquired disease of pigmentation which is presented by depigmented areas of different shape and sizes on the skin. In various researches it was reported that these defects in melanocytes occurred due to autoimmune pathway or the complex causation of oxidative stress and genetics. Material & Methods: In the present cross‑sectional prospective study 100 patients who were diagnosed with Leukoderma and controls who were not having depigmentation of skin and without any known clinical disease were enrolled for present study by simple random sampling. Written informed consent was taken from each study participant. Clearance from institutional ethical committee was also taken prior to the study. Results: The prevalence of psychiatric illness among leukoderma group was 22% and among 78% patients we did not found any psychiatric illness. The most common symptom was depression which was present among 22% of patients with Leukoderma and 18% patients with Leukoderma had anxiety symptoms. Among the control group depression was present in 5 % subjects and anxiety symptoms were present in 7% of subjects. The mean WHO-Quality of life scores was low among Leukoderma group in relation to the control group (p value <0.05). On correlation with psychiatric illness, observations were statistically non-significant (p > 0.05) with HAMA-A and HAMA- D. The observations were statistically significant (p < 0.05) with GHQ total and BSA score. Conclusion: Higher prevalence of psychitric morbidity among patients with leukoderma and it was found associated with duration of disease and BSA scores. The most common symptom was depression which was followed by anxiety symptoms. Key words: Leukoderma, psychiatric illness, anxiety, depression.
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