Background: Zinc is a divalent cation first isolated in 1509 and since then its importance has been increasingly recognised in human health and nutrition. Present study has been undertaken to confirm the association between maternal plasma or serum zinc concentration and birth weight.Methods: Present study was cross-sectional study conducted in tertiary care hospital. Newborns with a birth weight of < 2.5kg and their mothers labelled as study group while newborns with a birth weight of > 2.5kg and their mothers were considered as control group. The analysis for the serum concentration of zinc was done using the Atomic Absorption Spectrophotometric method (AAS), this method analytically the most reliable for routine assessment of serum zinc levels. The results deduced from the analysis were accordingly grouped to the study group / control group. We had a sub-group analysis based on the gestational age, as Preterm and Term.Results: Maternal serum levels of zinc 67.04 μg /dl±16.66, in the study group, was less as compared to the maternal serum levels of zinc in the control group with a mean level of 75.39 μg/dl±17.89. The results show a significant association between zinc levels and birth weight. Mean Maternal serum levels of zinc 67.04 μg /dl±16.66, in the study group, was less as compared to the maternal serum levels of zinc in the control group with a mean level of 75.39 μg/dl±17.89. The results show a significant association between zinc levels and birth weight.Conclusions: Present study showed a positive correlation of maternal zinc levels with birth weight and prematurity. Hence, we recommend routine zinc supplementation could be included with other nutritional supplements during pregnancy.
In the current study we intend to measure the effectiveness and protection of high and low dose oxytocin for rise of labour, on process of delivery. Materials and Methods: One hundred pregnant women needed growth of labor forinadequate uterine contractions, even 1 hour after ARM [If membranes intact],and cervical dilatation is at least 3 cm or more. These cases were selectedrandomly and were assigned to either a low dose (2.5 mU/min) or a high dose(5 mU/min) regimen. Study included equal number of primigravida and multigravida in each group. Results: High dose oxytocin group was associated with significant shorter duration of labor, as indicated by shortened augmentation to full dilatation and augmentation to delivery gap in primigravidae contrast to low dose group, but not in multigravdia. Both in multigravida and primigravdia maximum oxytocin dose was high with high dose regimen compared to low dose. Conclusion: High dose oxytocin is better to low dose oxytocin for labour augmentation for efficient dystocia in primigravdia. High dose oxytocin augmentation in primigravdia is connected with considerable decrease in first stage of labour without any unpleasant perinatal and maternal morbidity or mortality.
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