DNA microarray technology produces gene expression matrix that consists of an inexorably missing entries due to poor experimental procedures. The missing values are predicted in the matrix for gene expression data are considered to be essential, since most algorithms analyse the gene expression that usually needs a matrix without missing values. In order to address this issue, the present study biclustering Genetic based Simulated Annealing (Genetic SA) algorithm to predict the items that are missing in the gene expression data. The present study uses biclustering method that is considered to be essential for clustering the gene expression data. The performance evaluation shows that the proposed Genetic SA for gene data expression predicts the missing items in an accurate manner than the existing methods.
In this paper, liver abnormality is detected using an improved classification model that consists of series of process. The study reveals the liver condition to be normal or abnormal using the proposed system. The study uses both structural and statistical analysis, where both these analysis is combined with the process of classification. Initially, the noises are removed using Impulse Noise Removal and then the Segmentation is carried out using Gray Wolf Optimisation (GWO) algorithm. After the segmentation, the features are extracted through Local Binary Patters (LBP) Operator and then Artificial Neural Network Fuzzy Inference System (ANFIS) classifies the liver regions as malignant or benign. Various images collected from laboratories are used in both training and testing stages. The results are validated in terms of two different texture feature extractors namely, GLCM and LBP. The result shows that the proposed classifier using GLCM classifier obtains improved classified patterns than the existing methods.
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