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The next care to be taken, in respect of the Senses, is a supplying of their infirmities with instruments, and as it were, the adding of artificial organs to the natural...and as glasses have promoted our seeing, so 'tis not improbable, but that there may be found many mechanical inventions to improve our other senses of hearing, smelling, tasting and touching. " Robert Hooke English natural philosopher (1665) [1] Nothing could demonstrate more than this concept of Hooke with regards to replacement of all the senses by artificial means. Hooke was enthralled by spectacle correction itself and felt that the other senses could also be improved. No doubt the medical world has caught up with hearing aids and cochlear implants but in the real sense the restoration of sight to a blind is still in an experimental stage and the most daunting challenge in ophthalmic research.

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Phacotrabeculectomy provides effective and sustained visual recovery and adequate control of intraocular pressure as compare to conventional combined procedure.

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Background: Evaluation of penetrating keratoplasty in cases of pseudophakic bullous keratopathy with AC/PC IOL exchange. Methods: This retrospective study included 120 cases of pseudophakic bullous keratopathy managed over 9 years at three tertiary care eye centres followed up for 4 years. Cases were taken up for penetrating keratoplasty along within adjuvant procedures like IOL explantation and Secondary Posterior Chamber IOL implantation over the frill of posterior capsule. Results: Lens exchange with Penetrating Keratoplasty (PK) was done in 93 and PK without lens exchange in 27 cases. 25% required systemic steroids for 2-3 weeks. Re-grafting was performed in 5% and 85% attained moderate visual acuity. Conclusion: Intra ocular lens exchange and Posterior chamber IOL are suitable for penetrating keratoplasty in terms of optical clarity, graft survival and visual outcome.

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