, 721 (1984).Ferene iron reagent, 3-(2-pyridyl)-5,6-bis(2-(5-furyl sulfonic acid)-l,2,4-triazinc. disodium salt, n~onohydrate, has bccn synthesized and characterized. Results of a study of its complex formation with iron(ll) including A,,,.,,, E,,,.,,, and log K values are reported. [Traduit par Ic journal]

Determination of Thiamin 179 form a sulfonyl chloride and cyanamide hydrochloride.2. N-Alkyl substituted iso thioureas interact with chlorine under similar conditions to form sulfonyl chloride and the corresponding alkyl cyanamide derivatives.3. N-Aryl substituted iso thioureas interact with chlorine to give cyanamides containing chlorine substituted in the aryl grouping of the cyanamide.4. N, N' -Diarylisothioureas interact with chlorine to form halogenated diaryl ureas and sulfonyl chlorides.New Haven, Conn.

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Thiamin is reduced by sodium borohydride to a tetrahydrothiamin and a dihydrothiamin. Sodium trimethoxyborohydride converts thiamin chiefly into a lower melting dihydrothiamin from which the higher melting isomer can be obtained. Sulfite cleavage, desulfurization, physical data, hydrolytic deamination and yeast regeneration to thiamin show tetrahydrothiamin to be 4-methyl-5-~-hydroxyethyl-3-(2'-methyl-4'-amino-5'-methylenepyrimidyl)-thiazolidine. Ultraviolet and infrared spectra, potentiometric titration and other considerations suggest that the low melting dihydrothiamin is 4-methyl-5-~-hydroxyethyl-3-(2'-methyl-4'-amino-5'-methylenepyrimidyl)-4-thiazoline and the high melting isomer 8-methyl-3-(2'-methyl-4'-amino-5 '-methylenepyrimidy1)-octahydrofurano [ 1,2-d] thiazole.

An explanation of the inhibition of the metabolism of carbamates and other pesticides by methylenedioxybenzenes is proposed. Oxidative metabolism of the methylenedioxybenzene with transfer of hydride from the methylenedioxy group is postulated. If the resulting electrophilic benzodioxolium ion were to react with a nucleophilic group in a com-

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