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Tyrosyl-, histidyl-, asparaginyl-, and phenylalanyl-tRNAs from a spectrum of Morris hepatomas were compared to the same respective aminoacyl-tRNAs from normal rat liver by means of methylated albumin kieselguhr column chromatography. The tyrosyl-, histidyl-, and asparaginyl-tRNAs from hepatoma 3924A had altered elution profiles similar to those found earlier in Novikoff hepatoma. Hepatomas 9121, 9098, 3683F, and 5123C had altered phenylalanyl-tRNA profiles. Codon recognition properties of tyrosyl-A previous study of the tRNA obtained from the Novikoff hepatoma demonstrated pronounced differences in the MAK1 column elution profiles of tyrosyl-, histidyl-, and * From the

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