Evidence converges from a wide range of contexts to suggest that the causal beliefs held by an individual, or predominant in a group of individuals, are of considerable practical significance and theoretical interest. A good system for analysing naturally occurring expressions of causal belief would provide the possibility of testing and exploring this supposition without having to rely on possibly artificial questionnaire responses. A rationale for such a system is described and a study of the reliability of the coding procedure is reported. It has proved possible to formulate definitions of the five major dimensions identified in the attribution literature so that, while they are not all orthogonal, each provides unique information. The coding system is shown to have adequate reliability, and to generate substantial quantities of data. The findings from these data are generally in accordance with those obtained using more traditional methodologies, and provide substantive information about the subject population. The method is proposed as an effective technique for empirical investigations of the forms, stability and significance of naturally expressed causal beliefs.
The electrokinetic stability of washed normal human erythrocytes is discussed from the point of view of pH, ionic strength, and composition of the suspending medium. Many of the electrophoretic characteristics at low ionic strengths (sorbitol to maintain the tonicity), such as the isopotential points, are shown to arise principally from adsorption of hemolysate.
The concept of electrokinetically stable, metastable, and unstable states for the red cell at various ionic strengths is introduced in preference to the general term "cell injury." In the stable state which exists around pH 7.4 for ionic strengths >0.007, no adsorption of hemolysate occurs, in the metastable state reversible adsorption of hemolysate occurs, and in the unstable state, in which ionic strengths and pH ranges are outside the metastable range, the membrane undergoes irreversible hemolysate adsorption or more general hydrolytic degradation.
It is deduced from the equivalent binding of CNS, I, Cl, and F, the pH mobility relationships, and the conformation of the ionic strength data in the stable state to a Langmuir adsorption isotherm, that the membrane of the human erythrocyte behaves as a macropolyanion whose properties are modified by gegen ion association and in some instances by hemolysate adsorption.
The experimental results are insufficient to establish conclusively the nature of the ionogenic groupings present in the membrane interphase.
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