A histoanatomic study of the rotator cuff interval was done in 13 cadaveric specimens to investigate the relation of its ligamentous structures to the long head of the biceps tendon, with a special focus on revealing a stabilizing function. After macroscopic evaluation, the lateral half of the rotator cuff interval capsule was cut into three sections: medial, middle, and lateral. These sections were embedded in methacrylate, and then serial sections were made and stained for polarized light microscopy. The superior glenohumeral ligament was seen to form a fold having the macroscopic appearance of a U-shaped anterior suspension sling for the long head of the biceps tendon. Microscopic evaluation revealed an important role of the fasciculus obliquus in the roof of this sling. Fibers of the supraspinatus tendon join the posterosuperior part of the sling. The subscapularis tendon is not involved in this suspensory mechanism. As a result of these observations, we determined that the superior glenohumeral ligament and the fasciculus obliquus are the most important ligamentous reinforcements of a stabilizing sling for the long head of the biceps tendon in the rotator cuff interval. Their histologic appearance indicates they function to protect the long head of the biceps against anterior shearing stress. A lesion of this sling might lead to anterior instability of the biceps tendon.

IBD was associated with enhanced formation of AOPP, which differed between C and UC with respect to the relationship between rAOPP and disease activity, inflammatory and antioxidant response. These differences may reflect divergent ways that oxidative stress develops in CD and UC. The diagnostic power of rAOPP was insufficient for its clinical application.

No abstract

PON1 was reduced in IBD, despite treatment with antioxidant 5'-aminosalicylate derivatives. PON1 reflected disease activity, inflammation severity, and anemia but not lipid peroxidation. The diagnostic power of PON1 was insufficient for its clinical application.

MDA/TBARS are elevated in CD and may help to rule the disease out, while the combined evaluation with CRP may serve for CD confirmation. oxLDL and PP depended on substrate availability, decreased in CD.

BackgroundRevision in failed shoulder arthroplasty often requires removal of the humeral component with a significant risk of fracture and bone loss. Newer modular systems allow conversion from anatomic to reverse shoulder arthroplasty with retention of a well-fixed humeral stem. We report on a prospectively evaluated series of conversions from hemiarthroplasty to reverse shoulder arthroplasty.MethodsIn 14 cases of failed hemiarthroplasty due to rotator cuff deficiency and painful pseudoparalysis (in 13 women), revision to reverse shoulder arthroplasty was performed between October 2006 and 2010, with retention of the humeral component using modular systems. Mean age at the time of operation was 70 (56–80) years. Pre- and postoperative evaluation followed a standardized protocol including Constant score, range of motion, and radiographic analysis. Mean follow-up time was 2.5 (2–5.5) years.ResultsMean Constant score improved from 9 (2–16) to 41 (17–74) points. Mean lengthening of the arm was 2.6 (0.9–4.7) cm without any neurological complications. One patient required revision due to infection.InterpretationModular systems allow retainment of a well-fixed humeral stem with good outcome. There is a risk of excessive humeral lengthening.

The aim was to develop a German questionnaire for self-assessment of shoulder function equivalent to the Constant-Score (CS). To evaluate the retest reliability, the CS questionnaire was completed twice within 1 week by 47 patients prior to shoulder surgery. For validation the CS was assessed by the physician after the second self-test. The medium selectivity of the CS questionnaire at hospital admission was 0.47, the medium item difficulty 0.40, the test-retest reliability 0.675 ( p=0.000), the internal consistency of the questionnaire 0.80, and of the physician's CS evaluation 0.85. Construct, content, and discriminative validity of the questionnaire could be demonstrated. A high correlation of the patient-based questionnaire with the physician-assessed CS was found ( p=0.82). The statistical analyses demonstrated that the CS questionnaire is a reliable and valid instrument to evaluate the CS and can therefore be used for follow-up studies.

No abstract