Boston's Chinatown is an urban community surrounded by businesses, a university, a large medical centre, and an area zoned for "adult entertainment" called the Combat Zone. The overall goal of this exploratory study was to examine the temporal and geographic distribution of street crime in Boston's Chinatown using police crime reports from the years 1988 to 2004. Crime patterns were most notably associated with the presence of the adult entertainment area, known as the Combat Zone. However, despite the decline of adult businesses over the study period, we saw small limited reduction in property and violent crimes, suggesting that the decline of these businesses did not lead to large-scale short-term (,5 years) reductions in crime.

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Despite the advances in perinatal and neonatal care and use of newer potent antibiotics, the incidence of neonatal sepsis remains high and the outcome is still severe. For years, investigators have sought a test or panel of tests able to identify septic neonates accurately and rapidly in order to obtain an early diagnosis and develop a specific effective treatment for a successful outcome. In addition to the standard procedures (blood, CSF, and urine cultures, chest x-ray), such panels have included a combination of total and differential cell counts, total immature neutrophil counts, immature to total neutrophil ratio, platelet counts, and levels of acute-phase reactants and cytokines. Furthermore, the science of proteomics and genomics has been applied to the search for biomarkers, production of protein profiles and genetic polymorphisms that can rapidly help the prediction, early diagnosis, and treatment of human diseases, but, for now, data are as yet insufficient to confirm their validity.

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