Results show that RegCM3 reproduces the observed spatial structure of surface air temperature and precipitation well. Changes in mean temperature and precipitation in December-January-February (DJF) and June-July-August (JJA) during the middle and end of the 21st century are analyzed. Significant future warming is simulated by RegCM3. This warming becomes greater with time, and increased warming is simulated at high latitude and high altitude (Tibetan Plateau) areas. In the middle of the 21st century in DJF, a general increase of precipitation is found in most areas, except over the Tibetan Plateau. Precipitation changes in JJA show an increase over northwest China and a decrease over the Tibetan Plateau. There is a mixture of positive and negative changes in eastern China. The change pattern at the end of the century is generally consistent with that in mid century, except in some small areas, and the magnitude of change is usually larger. In addition, the simulation is compared with a previous simulation of the RegCM3 driven by a different global model, to address uncertainties of the projected climate change in China.climate change, regional climate model, China, numerical simulation, uncertainty
Citation:Gao X J, Shi Y, Zhang D F, et al. Climate change in China in the 21st century as simulated by a high resolution regional climate model.
The genetic loci affecting the commonly used BMI have been intensively investigated using linkage approaches in multiple populations. This study aims at performing the first genome‐wide linkage scan on BMI in the Chinese population in mainland China with hypothesis that heterogeneity in genetic linkage could exist in different ethnic populations. BMI was measured from 126 dizygotic twins in Qingdao municipality who were genotyped using high‐resolution Affymetrix Genome‐Wide Human SNP arrays containing about 1 million single‐nucleotide polymorphisms (SNPs). Nonparametric linkage analysis was performed with Merlin software package for linkage analysis using variance components approach for quantitative trait loci mapping. We identified a strong linkage peak at the end of chromosome 7 (7q36 at 186 cM) with a lod score of 4.06 which overlaps with that reported by a large multicenter study in western countries. Multiple loci showing suggestive linkage were found on chromosome 1 (lod score 2.38 at 242 cM), chromosome 8 (2.48 at 95 cM), and chromosome 14 (2.2 at 89.4 cM). The strong linkage identified in the Chinese subjects that is consistent with that found in populations of European origin could suggest the existence of evolutionarily preserved genetic mechanisms for BMI whereas the multiple suggestive loci could represent genetic effect from gene—environment interaction as a result of population‐specific environmental adaptation.
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