Design, Synthesis, and Biological Activity of Rigid Acetanilide Herbicides A series of rigid acetanilide compounds was synthesized to test the hypothesis of the intermediacy of an oxonium ion in the mechanism of action of the known acetanilide herbicides. The compounds did react with nulceophiles, although unexpected ring-opened products were obtained. The compounds prepared did not exhibit any significant biological activity in either preemergence or postemergence screens.
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