Departments of Anatornil, Stunford Untorrsity, S t a n f o~d , Cnlzfornici, i r t i d Vayne Unizc rsily Collcge of 1frdicime, Dc,troit, X~c 7 i i . q m SIXTEEIN FIGURES IlSTRODUCTIOSThe majority of reports on the developiiieiit of joints haw emphasized the early stages, and relatively little attention has been paid to cliaiiges during tlie later fetal niontlis aiicl the postnatal period of growth. That striking, unexplained changes d o occur is illustrated by the marked clifferences between fetal and adult sternoclioiidral joints (Gray and Garclner, '43). A more detailed knowledge of the preand postiiatnl development of these aiid otlier joints is obviously iiecessarjfor a better underi.;tanding of the physiological processes aiicl pathological changes wliicli take place in tlicni. As a result of their studies on the cllcvclopiiieiit of joints, several investigators have at tempted to relate dcvrlopneiitnl changes to either genetic or niechanical factors. IIeiikc and Reyher (1874) were among the first of these, and tlicp coiieluded that movement is the factor which deterniincs tlie form of articular structure. Tlicir conclusions u7ei.e later supported by Schulin (1879)' Hagen-Torn (1882), and Toriiiei. (1894).The developmerit of the kiiee has heen studied more tliaii that of any other joint. In 1878 Bernays published his Classical work oil its tlereloprneiit in man and other aninials mid Aided by a grant from the L)i,ision of Rcsenrclr Grants and Fellonships.

No abstract