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Spectra obtained with the Hubble Space T elescope Goddard High Resolution Spectrograph are combined with high-resolution optical spectra and UV spectra from Copernicus to study the abundances and physical conditions in the di †use interstellar clouds seen along the line of sight to the star 23 Ori. Multiple absorption components are present for each of several distinct types of gas, which are characterized by di †erent relative abundance and depletion patterns and physical conditions. Strong low-velocity (SLV) absorption, due to cool, moderately dense neutral gas and representing about 92% of the total N(H I), is seen for various neutral and singly ionized species at ]20 km s~1 km s~1. Most typically severely depleted species are less depleted by factors of 2È4, com-