Device-associated health care-associated infections (DA-HAI) are one of the significant threats to patient safety concerning increased morbidity and mortality, particularly in intensive care units (ICUs). Objectives: We aimed to assess deviceassociated infection (DAI) rates, microbiological profiles, and attributable mortality in ICUs from a large tertiary care hospital. Methodology: This retrospective surveillance study was done over a one-year period by applying the Centers for Disease Control and Prevention (CDC) and National Healthcare Safety Network (NHSN) case definitions for calculating ventilator-associated pneumonia (VAP), central line-associated bloodstream infection (CLABSI), and catheter-associated urinary tract infection. Results: A total of 2022 patients were hospitalized in ICUs and acquired 86 DAIs, with an overall rate of 4.4 DAIs per 1,000 device days. The most frequently recognized infection was VAP (55.8 %), followed by CAUTI (32.6%) then CLABSI (11.6%). The most commonly isolated organisms were Enterobacteriaceae (43%), followed by non-fermentative Gram-negative bacteria (41%) and Gram-positive cocci (12%). Multidrug resistance was identified in 80% of the isolates. The crude excess mortality for CLABSI (66.7%) was higher than VAP (45.4%) and CAUTI (19.5%). Conclusions: The high incidence rates of DA-HAIs together with the prevalence of antimicrobial resistance highlight the requirement to implement a comprehensive care-bundle approach program as well as an antimicrobial stewardship.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.