Considering the image quality and execution times, this method may be useful for reconstruction of low-dose clinical acquisitions. It may be of particular benefit to patients who undergo multiple acquisitions by reducing the overall imaging radiation dose and associated risks.

No abstract

The use of iterative reconstruction improves cone-beam optical CT image quality in many ways. The comparisons between OSC-TV and filtered backprojection presented in this paper demonstrate that OSC-TV can potentially improve the rendering of spatial features and reduce cone-beam optical CT artifacts.

Partial system matrix storage was shown to yield the lowest relative performance. On-the-fly ray tracing was shown to be the most flexible method, yielding reasonable execution times. A fully stored system matrix allowed for the lowest backprojection and OSC iteration times and may be of interest for certain performance-oriented applications.

No abstract