Phytochemical, toxicological and histo-pathological studies were carried out on the leaves and stem bark extracts of Grewia mo/lis, Boswe//ia da/zie//ii, Jatropha curcas and Pterocerpus erinaceus claimed to be of medicinal values in Nigeria. The soxhlet apparatus was used for extraction of the crude materials. The result revealed the presence of tannins, saponins, flavonoids, glycosides, balsam, phenols, terpenes, steroids and the absence of alkaloids in Grewia mo/lis (bark), Boswe//ia da/zie//ii (leaf) and Pterocarpus erinaceus (bark) as well as cyanogenic glycosides in all the plant materials. Toxicological result showed that the plant is safe for human consumption but with caution having produce LDsoat 1500 mg/kg body weight. The extracts showed no structural effects on the liver and heart.dn'the kidney however, the convoluted tubules were filled with fluids, which suggested that the extract should be used with caution on patients with renal failure. The plants therefore possess some important biological activities that could be harnessed and employed beneficially in the management of viral and bacterial infections.
The effects of improved method of extraction on the physicochemical, mycological and stability of crude Canarium Schweinfurthii fruit oil were studied. The extracted oils were then stored at 25±5 o C for 24 months with samples analyzed at 6months interval for; pH, saponification value, acid value, peroxide value and iodine number. Similarly, enumeration and identification of fungi species was determined using standard mycological procedures. The results showed that crude Canarium Schweinfurthii fruit oil obtained by the improved method of extraction had better quality and stability parameters than the traditional method extracted oil.
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