Green betel (Piper betle L.) leaf contains anti-thrush, anti-cough, astringent, and antiseptic chemicals such as saponins, flavonoids, polyphenols, and essential oils. Hand sanitizer can also be used as an antiseptic agent, which is a more practical option. The purpose of this study was to see how the composition of green betel leaf extract made by infusion affected its physical properties and bacterial inhibition. Hand sanitizer samples were made using different concentrations of green betel leaf extract (10 - 25 wt%) with and without the addition of tea tree essential oil. Sample testing included organoleptic tests, physical properties tests, and effectiveness tests on the growth of Escherichia coli bacteria. The results showed that the best composition was found to be at a concentration of 10 wt% green betel leaf extract without the addition of essential oil, with pH ranging from 5.2 to 5.8 and viscosities ranging from 1.32 to 1.99 cps, in the form of a watery gel and a clear yellow color. Meanwhile, hand sanitizer sensitivity testing revealed that none of the samples could inhibit the growth of Escherichia coli bacteria. This indicates that the concentration of green betel leaf extract in the sample is still insufficient to inhibit bacterial growth.
Sweet potato (Ipomea batatas) is a plant found mostly in America. The rich content of flavonoid in sweet potato which acts as anti-oxidant can prevent premature aging and can also protect cells from damages caused by free-radicals. Flavonoid possesses an anti-bacterial nature which can disturb the cell wall function of bacteria through the mechanism of complex formation with extracellular protein. This article is written using narrative review method through electronic scientific article, journal, and textbook. Authors identified 16 articles which published from 2010-2020. Out of 16 articles, 11 of them were in match to the criteria and the results were found that the physical characteristics of anti-acne spray gel can be determined through the dispersibility test, organoleptic test, adhesivity, dry time, and stability test. For the biological characteristic of spray gel can be done using Well method for the Propinibacterium acnes. Sweet potato-based spray gel possesses physical and biological characteristic which can slows bacterial growth significantly compared to green tea shoots and purple leaf.
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