Background: Corona virus disease 2019 has taken a huge toll over health infrastructure and care all across the world. This article depicts our experience of COVID-19 in pregnant women and analyses maternal and neonatal outcome of same in first and second wave of this pandemic. Aim and objectives of the study were to compare the demographic characteristics, presenting features and fetomaternal outcome in COVID positive pregnant women in first v/s second wave in a tertiary care hospital.Methods: The RTPCR COVID-19 positive pregnant women admitted during the period April-2020 to March-2021 were considered in 1st wave of COVD-19 and that from April-2021 till June-2021 as 2nd wave of COVID-19. Data like baseline characteristics, past medical, obstetric history, clinical presentation, laboratory results, imaging findings, management modalities, maternal and neonatal outcome were analysed and compared.Results: Peak of 1st wave of COVID-19 was found during the months of July-September 2020, while of 2nd in April-June 2021. Most women presented with COVID-19 RTPCR positive were asymptomatic both in 1st and 2nd wave. Though most patients were managed on room air in both waves, 6.52% and 9.38% were on oxygen, 1.09% and 10.94% were managed with mechanical ventilation and BIPAP in 1st and 2nd wave respectively. There was significant (p<0.05) increase in maternal deaths in the 2nd wave (7.03%) as compared to 1st wave (1.09%).Conclusions: A significantly large number of patients were affected in 2nd wave of COVID-19 pandemic with more morbidity and mortality. Neonatal population remained relatively unaffected in both waves.
Background: Vaginal pH change also has a role in preterm delivery which suggests that it has a role in influencing cervical ripening. The aim of this study to evaluated the effect of vaginal pH on cervical ripening with dinoprostone (PGE2) gel between rural and urban primegravida.Subjects and Methods:This is hospital based comparative study done on 50 pregnant women admitted in labour room for induction of labour and fulfilling inclusion/exclusion criteria at Obstetrics and gynaecology department, RNT Medical college, Udaipur. Group I included patients with vaginal pH <4.5 and Group II included vaginal pH>4.5. A vaginal examination was then performed to determine the Bishop's score. After ruling out all contraindications Dinoprostone gel was applied endocervically.Results:Our study showed that mean age of pregnant women was 25.10 yrs in rural patients and 24.56 yrs in urban patients. The high vaginal pH (>4.5) was more in urban pregnant women as compare to rural pregnant women, it was statistically non-significant (P=0.1062) and low vaginal pH (≤4.5) was more in rural as compare to urban. The augmentation required, time to active labor & time to induction delivery interval was not statistically significant (P=0.4276, P=0.2341 & P=0.1445 respectively) in between rural & urban pregnant women. LSCS was more common in rural as compare to urban pregnant women, but did not statistically significant (P=0.1945 NS).Conclusion: We concluded that higher vaginal pH more often responds to a single induction and is more often associated with vaginal deliveries rather than non-progress of labor.
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