Abstract::
Lymphatic system is the secondary circulation system of the human body, after the systemic circulation. Various
problems, including first-pass metabolism through oral administration of medicines, can be resolved by lymphatic targeting.
Lymphatic absorption has been explored in detail and studies reveal the improved bioavailability of medicines. In the case
of cancer, AIDS, and various other health problems, lymphatic targeting has been focused on due to the fact that lymph
nodes are involved greatly in tumor metastasis. This article reviews the lymphatic absorption and its exploration in the
treatment of various health problems. The physiology of the lymphatic system, the mechanisms of absorption, and the
various formulation systems suitable for lymphatic absorption have been discussed. Some recent novel approaches like
hydrodynamically driven device (HDD) and carbon nanotubes for lymphatic delivery have also been appraised.
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