Biomedical text summarization (BTS) is proving to be an emerging area of work and research with the need for sustainable healthcare applications such as evidence-based medicine practice (EBM) and telemedicine which help effectively support healthcare needs of the society. However, with the rapid growth in the biomedical literature and the diversities in its structure and resources, it is becoming challenging to carry out effective text summarization for better insights. The goal of this work is to conduct a comprehensive systematic literature review of significant and high-impact literary work in BTS with a deep understanding of its major artifacts such as databases, semantic similarity measures, and semantic enrichment approaches. In the systematic literature review conducted, we applied search filters to find high-impact literature in the biomedical text summarization domain from IEEE, SCOPUS, Elsevier, EBSCO, and PubMed databases. The systematic literature review (SLR) yielded 81 works; those were analyzed for qualitative study. The in-depth study of the literature shows the relevance and efficacy of the deep learning (DL) approach, context-aware feature extraction techniques, and their relevance in BTS. Biomedical question answering (BQA) system is one of the most popular applications of text summarizations for building self-sufficient healthcare systems and are pointing to future research directions. The review culminates in realization of a proposed framework for the BQA system MEDIQA with design of better heuristics for content screening, document screening, and relevance ranking. The presented framework provides an evidence-based biomedical question answering model and text summarizer that can lead to real-time evidence-based clinical support system to healthcare practitioners.
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