Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nevoid condition characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities, having distinct porokeratotic histopathological features. The lesions usually present at birth or in childhood. We present here a case of late-onset PEODDN in a 23-year-old man who had lesions on the palm, forearm, arm and the chest along the lines of Blaschko, strictly localized to the left side of the body.
Nevus lipomatosus cutaneous superficialis (NLCS) is a benign dermatosis, histologically characterized by the presence of mature ectopic adipocytes in the dermis. We hereby report a case of a 10-year-old boy who presented with multiple huge swellings on the scapular regions and lower back. The lesions were surmounted by small papules, along with peau-d orange appearance at places. Histology showed features consistent with NLCS. The case is being reported for the unusual clinical presentation.
Measurement of birthweight is an indicator of community health. The mean birthweight (MBW) of babies born in 1963, 1983 and 1986 were measured in 2254, 3550 and 3368 babies, respectively. Mean (SD) birthweight was found to be 2652 (553) g in 1963, 2724 (502) g in 1983 and 2726 (478) g in 1986. There was a rise in MBW (72 g) between 1963 and 1983 and a reduction in the percentage incidence of low birthweight from 34.29% to 26.06%. A change in birthweight distribution (was also seen, except in extreme weight groups. The improvement in birthweight is statistically significant (p less than 0.001). A trend for increase has been noticed in birthweights, and the mean birthweight values are the same as the national average.
Bullous pemphigoid is an autoimmune blistering disease that is rare in childhood. Pemphigoid nodularis is a variant of BP that is exceedingly rare in children. Pemphigoid nodularis is characterized by overlapping clinical features of both prurigo nodularis and BP. We report here a case of pemphigoid nodularis in an 11-year-old boy.
Objective
To develop and validate birthweight prediction models using fetal fractional thigh volume (TVol) in an Indian population, comparing them with existing prediction models developed for other ethnicities.
Methods
A prospective observational study was conducted among 131 pregnant women (>36 weeks) attending a tertiary hospital in New Delhi, India, for prenatal care between December 1, 2014, and November 1, 2016. Participants were randomly divided into formulating (n=100) and validation (n=31) groups. Multiple regression analysis was performed to generate four models to predict birthweight using various combinations of two‐dimensional (2D) ultrasonographic parameters and a three‐dimensional (3D) ultrasonographic parameter (TVol). The best fit model was compared with previously published 2D and 3D models.
Results
The best fit model comprised biparietal diameter, head circumference, abdominal circumference, and TVol. This model had the lowest mean percentage error (0.624 ± 8.075) and the highest coefficient of determination (R2=0.660). It correctly predicted 70.2% and 91.6% of birthweights within 5% and 10% of actual weight, respectively. Compared with previous models, attributability for the 2D and 3D models was 0.65 and 0.55, respectively. Accuracy was −0.05 ± 1.007 and −2.54 ± 1.11, respectively.
Conclusion
Models that included TVol provided good prediction of birthweight in the target population.
Lupus erythematosus-lichen planus (LE-LP) overlap syndrome is an uncommon disorder with clinical, histological and/or immunopathological features of both diseases. We report a case of LE-LP overlap syndrome in a patient with HIV infection. To the best of our knowledge, LE-LP overlap syndrome with HIV infection has never been reported in literature.
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