Dhaka, the one of the megacities in the world have been facing the pressure of new development and redevelopment due to rapid socioeconomic development. Like the other part of the city in old Dhaka, this urban renewal is misunderstood as the process of demolition-reconstruction of old buildings and historical sites. Change in land use pattern, land scarcity, increased land value, lack of mature theoretical guidance and the awareness of preservation the old part of the city is losing its identity. This kind of development not only affecting the city fabric but also destroying the vernacular built environment, cultural values and collective memory of habitants. Introduction of heritage tourism and development of tourist trails in different part of the old city may become an effective and sustainable measure to protect the heritage sites and old fabric of the city. Heritage tourism not only has a positive effect on economic development activities but it also promotes and protects the intangible heritage resources. The study tries to explore some different ways in which tourist trail and heritage tourism can be developed in old Dhaka. Additional emphasis will placed on investigating how tourism can be used to promote awareness among local communities and the importance of assuring a balance between responsible tourism and the preservation and protection required for heritage sites.
Background: Migraine is the most common cause of severe recurrent headache in children. Flunarizine (FNZ) is safe and effective drug for prevention of migraine in children. Topiramate (TPM) is also successful as a preventive drug for migraine in children on randomized, double-blind, placebo-controlled trials.
Objective: This study was done to observe the efficacy of Topiramate and also perform a comparison TPM and FNZ in patients with migraine of severe intensity in our situation.
Materials & Methods: This was a randomized controlled trial done from January to July, 2018. This study was carried out in the OPD of Paediatric Neurology department, National Institute of Neurosciences, (NINS) Dhaka. Forty Children, 5-15 years old diagnosed as migraine with/without aura with severe intensity were randomized either as in study group (TPM treatment group) and control group (FNZ treatment group). Primary end point of the study was to find out the efficacy and safety of both TPM and FNZ after 4 months of treatment.
Result: Post-treatment frequency of headache/month was significantly decreased in both groups (within group, p <0.001). There was no significant difference considering pre and post-treatment frequency of headache/month between two treatment groups. (pre-treatment p- 0.333 and post-treatment p- 0.401). Adverse events were not significantly different between the groups p<0.387.
Conclusion: Topiramate is equally efficacious as Flunarizine in prophylactic treatment of severe migraine in children.
Bangladesh J Child Health 2020; VOL 44 (3) :153-156
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is relatively rare in children. Moreover, atypical presentation remains a diagnostic challenge for physician. Early recognition and proper immunomodulatory therapy is important for favorable outcomes with prevention of progressive course. We report a case with atypical CIDP. The aim was to focus on the diagnostic difficulties and the importance of recognizing this treatable condition.
Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 64-66
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