Background
Non-paroxysmal atrial fibrillation (AF) has a complex pathophysiological process. The standard catheter ablation approach is pulmonary vein isolation (PVI). The additional value of complex fractionated electrogram (CFAE) ablation is still unclear. We aimed to investigate the additional value of CFAE ablation for non-paroxysmal AF.
Methods
We performed a systematic review and meta-analysis of randomized controlled studies up to May 2020. Articles comparing pulmonary vein isolation (PVI) plus CFAE ablation and PVI alone for AF were obtained from the electronic scientific databases. The pooled mean difference (MD) and pooled risk ratio (RR) were assessed.
Results
A total of 8 randomized controlled trials (RCTs) including 1034 patients were involved. Following a single catheter ablation procedure, the presence of any atrial tachyarrhythmia (ATA) with or without the use of antiarrhythmic drugs (AADs) between both groups were not significantly different (RR = 1.1; 95% confidence interval [CI] = 0.97–1.24; p = 0.13). Similar results were also obtained for the presence of any ATA without the use of AADs (RR = 1.08; 95% CI = 0.96–1.22; p = 0.2). The additional CFAE ablation took longer procedure times (MD = 46.95 min; 95% CI = 38.27–55.63; p = < 0.01) and fluoroscopy times (MD = 11.69 min; 95% CI = 8.54–14.83; p = < 0.01).
Conclusion
Additional CFAE ablation failed to improve the outcomes of non-paroxysmal AF patients. It also requires a longer duration of procedure times and fluoroscopy times.
Background
Atrial fibrillation (AF) is correlated with a poor biventricular pacing and inadequate response to cardiac resynchronization therapy (CRT). Biventricular pacing improvement can be achieved by conducting the atrioventricular junction ablation (AVJA). We aimed to investigate the benefit of AVJA for permanent AF and heart failure with reduced ejection fraction (HFrEF) patients receiving CRT.
Methods
In August 2020, a systematic review and meta-analysis study comparing CRT plus AVJA versus CRT for permanent AF and HFrEF patients was conducted. Relevant articles were identified through the electronic scientific database such as ClinicalTrials.gov, ProQuest, ScienceDirect, PubMed, and Cochrane. The pooled risk ratio (RR) and pooled mean difference (MD) were estimated.
Results
A total of 3199 patients from 14 cohort studies were involved in this study. Additional AVJA reduced cardiovascular mortality (RR = 0.75, 95% confidence interval [CI] = 0.61 to 0.93, P < 0.01) in permanent AF and HFrEF patients receiving CRT. Biventricular pacing rate was higher in CRT plus AVJA group (MD = 8.65%, 95% CI = 5.62 to 11.67, P < 0.01) than in CRT alone group. The reverse remodeling characterized by the reduction of left ventricular end-diastolic diameter (LVEDD) was greater in the CRT plus AVJA group (MD = −2.11 mm, 95% CI = −3.79 to −0.42, P = 0.01).
Conclusion
In permanent AF and HFrEF patients receiving CRT, AVJA effectively increased the biventricular pacing rate. Adequate biventricular pacing rate provided a better response to the CRT marked by the greater ventricular reverse remodeling and survival from cardiovascular mortality.
Penelitian ini bertujuan merancang dan membangun aplikasi virtual reality gedung jurusan Teknologi Informasi Politeknik Negeri Padang berbasis Android. Metode penelitian yang digunakan adalah penelitian kualitatif dimana strategis yang digunakan adalah Design and Creation. Penelitian ini menggunakan metode pengumpulan data observasi. Pengujian yang digunakan adalah menggunakan VR BOX. Hasil dari penelitian ini berupa aplikasi Virtual Reality Gedung Teknologi Informasi yang dapat menjadi media penyampaian informasi terhadap perguruan tinggi. Aplikasi ini sudah memvisualisasikan objek gedung beserta properti didalam gedung Teknologi Informasi, desain aplikasi menarik, informasi yang disajikan sebatas penetahuan umum. Virtual dapat berjalan dalam objek gedung dengan menggunakan kontrol pada kamera dan user mengendalikan untuk memulai atau berhenti.
Cardiovascular disease is the major causes of death in the world. Hypertension and diabetes mellitus are the important risk factors for cardiovascular disease. The prevalence of hypertension and diabetes mellitus is higher in the elderly population. Promotive and preventive efforts for the occurrence of hypertension and diabetes mellitus are the important strategies for preventing cardiovascular disease in elderly population. This was a social activity program developingthe preventive strategy against cardiovascular disease and improving of the quality of life of the elderly. This activity program was attended by 66 elderly participants routinely participated in the Panti Sosial Tresna Werdha Puspa Karma, Mataram. This program were consisted of counseling and healthy heart gymnasticsregularly every week for 3 months. The parameters taken in this event are height, body mass index (BMI), abdominal circumference, systolic and diastolic blood pressure, and serum fasting blood glucose (GDP) levels at the beginning and end of the programin order to assess the success of this program in reducingthe risk of suffered from cardiovascular disease. There were significant differences in the mean of body weight, BMI, abdominal circumference, systolic and diastolic blood pressure, and serum GDP levels between the the beginning and end of the programs (p<0.05). This social activity program reduced effectively the risk of cardiovascular disease in the elderly.
Development of the coordination system requires the dataset because the dataset could provide information around the system that the coordination system can use to make decisions. Therefore, the capability to process and display data-related positions of objects around the robots is necessary. This paper provides a method to predict an object’s position. This method is based on the Indoor Positioning System (IPS) idea and object position estimation with the multi-camera system (i.e., stereo vision). This method needs two input data to estimate the ball position: the input image and the robot’s relative position. The approach adopts simple and easy calculation technics: trigonometry, angle rotations, and linear function. This method was tested on a ROS and Gazebo simulation platform. The experimental result shows that this configuration could estimate the object’s position with Mean Squared Error was 0.383 meters. Besides, R squared distance calibration value is 0.9932, which implies that this system worked very well at estimating an object’s position.
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