No abstract

Croton argyrophylloides Muell. Arg., from the Euphorbiaceae family, popularly known as marmeleiro prateado or sacatinga, is a plant from the Caatinga biome commonly found in Brazil’s northeastern region. The present study aimed to evaluate the antioxidant activity of the species. The phytochemical study was performed through qualitative analysis of chemical constituents and quantitative determination of the total phenol content through the Folin-Ciocalteu test. The qualitative and quantitative antioxidant tests were performed using the DPPH method (2.2 diphenyl-1-picryl hydrazil) and ferric reducing antioxidant power (FRAP). The minimum inhibitory concentration (MIC) was determined by microdilution in 96-well plates. The ethanolic extract of the leaves of C. argyrophylloides manifested antioxidant action in the quantitative DPPH test with a significant bioactivity of 84.70 AAO% in 500 µg/mL, with an EC50 of 236.79. The content of total phenolic compounds was 946.06 mg of gallic acid equivalents/g of sample, and total flavonoids was 58.11 mg of quercetin equivalents/g of sample, the result obtained for FRAP was 15294.44 µM Trolox/g of sample and ABTS was 718 μM Trolox of sample. The prospecting of the chemical constituents of the leaves of C. argyrophylloides revealed the presence of the main compounds that manifests the antioxidant activity and it was proven by the DPPH method that there is antioxidant activity in the analyzed sample, in addition to demonstrating a significant content of phenolic compounds and total flavonoid content in the species, which corroborates the antioxidant activity of the plant sample. The leaf extracts presented growth inhibition halos of 10 and 12 mm upon Staphylococcus aureus ATCC 25923.

A utilização de sementes de qualidade, associada à adubação nitrogenada aplicada em doses e momentos adequados, pode aumentar a produtividade e o potencial fisiológico das sementes produzidas. Neste sentido, objetivou-se avaliar o efeito do vigor de sementes utilizadas na semeadura associado a combinações de doses e épocas de aplicação de nitrogênio sobre a produtividade e a qualidade fisiológica de sementes de trigo. O experimento foi conduzido com a cultivar BRS Gralha-Azul, sob delineamento de blocos casualizados em esquema fatorial 2x7, com quatro repetições. Os tratamentos consistiram em dois níveis de vigor de sementes (alto e baixo) associados a sete combinações de doses e aplicação da adução nitrogenada (N1- sem N; N2- 40 kg ha-1 de N no perfilhamento; N3- 80 kg ha-1 de N no perfilhamento; N4- 40 kg ha-1 de N na semeadura; N5- 80 kg ha-1 de N na semeadura; N6- 40 kg ha-1 de N na semeadura e 40 kg ha-1 de N no perfilhamento; N7- 20 kg ha-1 de N na semeadura e 60 kg ha-1 de N no perfilhamento). Foram avaliados: germinação, primeira contagem da germinação, comprimento e massa seca de plântulas, emergência de plântulas em areia, índice de velocidade e emergência, condutividade elétrica, massa de mil sementes e produtividade de sementes. A adubação com 20 kg ha-1 de N na semeadura e 60 kg ha-1 de N no início do perfilhamento foi o mais eficiente para a produção de sementes vigorosas da cultivar BRS Gralha-Azul. Sementes com alto vigor apresentam melhor potencial fisiológico. Os níveis de vigor de sementes e as combinações de épocas de aplicação e doses de nitrogênio não alteram a produtividade da cultura e a massa das sementes produzidas.

In Brazil, American visceral leishmaniasis (AVL) has become a public health concern due to its high incidence and lethality. This study aimed to analyze the clinical, epidemiological, and laboratory aspects of AVL in a state of Brazil. This descriptive, cross-sectional, retrospective, and quantitative study of notified cases of AVL was carried out in Alagoas between 2008 and 2017 from data obtained from DATASUS/SINAN. Sociodemographic, clinical, and laboratory variables were analyzed. A descriptive analysis was performed using absolute values and valid percentages, using tables and/or graphs. Data processing was performed using Stata 12.0®. Results with P <0.05 were considered statistically significant. During the study period, 352 cases of AVL were reported, of which 6.82% died and 38.92% had met a cure criterion. Male patients were predominant (66.76%). Of the total infected patients, 16.76% had attended only the 1st to the 4th grades, with those most affected aged 1 to 4 years (28.69%). Laboratory diagnostic criteria were most commonly used to confirm the notified cases (76.42%), whereas 51.70% and 8.52% of the cases had positive parasitological and immunofluorescence diagnoses, respectively. Finally, the study showed a higher prevalence of the disease in children, men and in rural residents. Although with low lethality, the expressive frequency of AVL in the State of Alagoas was still verified, since there was an increase in the number of cases during the years of the study.