NiO nanoparticles are biosynthesized using Sageretia thea (Osbeck.) aqueous leave extracts and their biological activities are reported. Nanoparticles (∼18 nm) were characterized through XRD, ATR-FTIR, EDS, SAED, HR-SEM/TEM and Raman spectroscopy. Antibacterial activity was investigated against six pathogenic bacterial strains (gram positive and gram negative) and their corresponding minimum inhibitory concentrations (MICs) were calculated. UV-exposed nanoparticles were investigated to have reduced MICs relative to the NiO nanoparticles have not been exposed to UV. Moderate linear fungal growth inhibition was observed while Mucor racemosus (percentage inhibition 64% ± 2.30) was found to be most susceptible. Cytotoxicity was confirmed using brine shrimps lethality assay (IC 42.60 μg/ml). MTT cytotoxicity was performed against Leishmania tropica-KWH23 promastigotes and amastigotes revealed significant percentage inhibition across the applied concentrations. IC values were calculated as 24.13 μg/ml and 26.74 μg/ml for the promastigote and amastigote cultures of Leishmania tropica. NiO nanoparticles were found. Moderate, antioxidant potential was concluded through assays like DPPH, TAP and TAC. Furthermore, protein kinase inhibition and alpha amylase inhibition is also reported.

Aqueous floral extracts of Callistemon viminalis were used to synthesize FeO nanoparticles (IONPs) which were intensively characterized through UV-vis, X-ray diffraction, HR-SEM/HR-TEM, Fourier- transform infrared spectroscopy (FTIR) and energy dispersive X-ray spectroscopy (EDS). Their physical properties were studied in response to different annealing temperatures. It was observed that the increase in the annealing temperature produced small-sized nanoparticles. The nanoparticle size was calculated as 32, 26 and 22 nm for annealing at 300, 400 and 500 °C, respectively. The magnetic nature of the bioinspired IONPs was revealed by superconducting quantum interference device (SQUID). Their antibacterial potential was investigated against nine pathogenic bacterial strains (gram positive and gram negative) using disc diffusion method while their MIC was calculated using broth dilution assay. Bioinspired IONPs were found to be highly effective against HepG2 cells (IC=20 µg/mL). Moderate antileishmanial activities against the promastigotes and amastigotes cultures are reported. Moderate acetylcholine esterase (AchE), butylcholine esterase (BchE) and α-Glycosidase inhibition are reported. Additional assessment of the biocompatibility was performed using haemolytic activity on the freshly isolated human red blood cells and macrophages. Furthermore, the antioxidant activities, including TAC, DPPH and TRP were also performed. Our results indicate that the biogenic and magnetic FeO can be used for diverse biomedical applications.

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We report an eco-friendly synthesis of α-Cr 2 O 3 nanoparticles (NPs) using Callistemon viminalis (Bottle Brush) flower extracts as an efficient reducing and capping agent. NPs of sizes 15 nm and 17 nm were synthesized by annealing them at 400°C and 500°C, respectively, which were characterized by X-ray diffraction, UV-Vis, Fourier transform-infrared, high-resolution-transmission electron microscopy/scanning electron microscopy, SAED, energy-dispersive X-ray spectroscopy and SQUID. Microplate-based assay was used for examining antibacterial potential against 12 pathogenic bacterial strains, and their minimum inhibitory concentrations were calculated. MTT cytotoxic assay was accomplished on Leishmania tropica amastigotes and promastigotes, which revealed IC 50 values of 44 μg/ml and 10.56 μg/ml, respectively. An IC 50 value of 46.32 μg/ml was obtained for HepG2 cancer cells. Enzyme inhibition studies indicated good acetylcholinesterase, moderate butyrylcholinesterase and low alpha-glucosidase inhibition. Hemolytic assay indicated hemocompatibility at low concentration. In addition, good DPPH radical scavenging and moderate reducing power and total antioxidant potential was revealed by α-Cr 2 O 3 NPs.

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Background: In recent years, the occurrence and fate of environmental pollutants has been recognized as one of the emerging issues in environmental chemistry. A survey documented about a wide variety of these pollutants, which are often detected in our environment and these are major cause of shortened life spans and the global warming. These pollutants include toxic metal, pesticides, fertilizers, drugs and dyes released into soil and major water bodies. The presence of these contaminants causes major disturbance in eco-system’s balance. To tackle these issues many technological improvements are made to detect minute contaminations. The latest issue being answered by the scientists is the use of green nano materials as sensors which are economical, instant and give much better results at low concentrations and can be used for the field measurements resulting in no dangerous by-product that could lead to more environmental contamination. Nano materials are known for their wide band gap, enhanced physical and optical properties with option of tuneablity as per need, by optimizing certain parameters. They are proved to be good choice for analytical/optical sensors with high sensitivity. Objective: This review holds information about multiple methods that use green nanomaterials for the analytical assessment of environmental pollutants. UV-Vis spectrophotometry and electrochemical analysis using green and reproducible nanomaterials are the major focus of this review article. To date, there are number of spectrophotometric and electro chemical methods available that have been used for the detection of environmental pollutants such as toxic metals, pesticides and dyes. Conclusion: The use of nanomaterials can drastically change the detection limits due to having large surface area, strong catalytic properties, and tunable possibility. With the use of nano materials, lower than the marked limit of detection and limit of quantification were seen when compared with previously reported work. The used nano-materials could be washed, dried, and reused, which makes the methods more proficient, cost effective and environmentally friendly.

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