Background: Tumours and tumour like lesions of skin have overlapping clinical presentation and sometimes pose a diagnostic difficulty on clinical ground alone. Histopathological examination although helpful to arrive at correct diagnosis, at times may be treacherous and may require ancillary tests such as Immunohistochemistry.Materials and Methods: The study was conducted at Department of Pathology of Tribhuvan University Teaching Hospital. It was a one year prospective study which enrolled 238 cases of skin biopsies after histopathological confirmation of tumours and tumour like lesions. The specimens were processed by standard method and Hematoxylin and Eosin stained sections were examined. Data entry and analysis was done by using SPSS 20 version.Results: Epidermal cyst was commonest lesion (11.8%). Among benign tumours squamous papilloma was most frequent while Pilomatricoma and Spiradenoma were most common adnexal tumour. Squamous cell carcinoma constituted 41.8% and was commonest malignant tumour followed by basal cell carcinoma (30.2%). Benign tumours were common in 11-30 years of age, malignant tumours in 61-80 years of age while tumour like lesions were common in 21-30 years of age.Conclusion: Squamous papilloma and squamous cell carcinoma was the most common benign and malignant tumour respectively. Benign adnexal tumours exceeded malignant one and were seen in third decade of life. Epidermal cyst was the commonest tumour like lesions followed by dermoid cysts.
Ovarian hemangiomas are uncommon benign vascular tumors of ovary. Most of them are asymptomatic and detected incidentally during surgery. Authors report a case of 41 years female, parity 2; with complain of lower abdominal pain for 6 months. Ultrasonography showed a cystic lesion at right adnexa with a heterogeneously echogenic component within and devoid of internal vascularity. Laparoscopic right adnexal cystectomy was done, which on histopathological examination demonstrated features of cavernous hemangioma replacing the ovarian parenchyma. As surgical excision is treatment of choice, correct diagnosis is essential to avoid unnecessary radical surgery and treatment.
Collision tumors are composed of two histologically distinct neoplasms in the same organ without intermixture of cell types. The co-occurrence of a serous adenocarcinoma with a mature cystic teratoma is very rare. We present here the case of a 48 years married female with bilateral high grade serous carcinoma of the ovary with left sided mature cystic teratoma.Asian Journal of Medical Sciences Vol.9(4) 2018 61-64
Colon carcinoma spreads locally around the intestine wall and can undergo distant metastasis via the hematogenous or lymphatic spread. It rarely metastasizes to the female genital tract and is not fully reported to involve a uterine leiomyoma. Herein we report such an unusual case of a 27 years female a known case of sigmoid colon adenocarcinoma who presented with abdominal pain with bilateral adnexal mass and per vaginal bleeding. Exploratory laparotomy with bilateral resection of ovaries with subsequent polypectomy was done, which on histopathology, it revealed metastatic adenocarcinoma in bilateral ovaries and submucosal leiomyoma. Hence, a lesion with dimorphic histomorphology should be carefully evaluated to rule out the possibility of malignant-to-benign tumor-to-tumor metastasis.
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