AIM: We aimed to explore whether there is difference in terms of Retinal Nerve Fiber Layer (RNFL) thickness, macula thickness and anterior segment structures of the eye between children and adolescents with ADHD and healthy controls. METHOD: Children and adolescents aged 8-16 years who were admitted to the Child Psychiatry outpatient clinic of Ahi Evran University Hospital diagnosed with ADHD constituted the study group. Exclusion criteria included patients who had any systemic/ocular or psychiatric disorder other than ADHD and patients who had any psychopharmacological treatment. Participants in the control group were children and adolescents who applied to the outpatient clinic of Ophthalmology at the same hospital with no chronic medical or psychiatric disorder. Groups were compared in terms of central macular thickness, retinal nerve fibre layer thickness (RNFL), central corneal thickness, corneal diameter, mean corneal radius of curvature, anterior chamber depth, and axial length using Optical Coherence Tomography (OCT) and Optical Biometry. RESULTS: Data obtained from the measurements of 60 eyes of 30 patients with ADHD and 60 eyes of 30 patients of the control group were evaluated. Groups were similar in terms of age and gender. Corneal thickness (p = 0.001) and axial length (p = 0.04) values were significantly higher in ADHD group while the mean corneal curvature radius (p = 0.03) was significantly lower in ADHD group than in controls. No significant difference was observed between groups in terms of RNFL thickness, macular thickness, the corneal diameter, and anterior chamber depth measurements. CONCLUSION: In recent years, the use of OCT in neuropsychiatric diseases has increased the interest in identifying possible biomarkers and the elucidation of neurodegenerative and neurodevelopmental mechanisms that contribute to the nature of these diseases. Differences in the ophthalmic anatomical structures observed between healthy controls and cases with ADHD, which is a neurodevelopmental disorder, need to be supported by longitudinal studies with a larger sample and using OCT in connection with brain imaging.
Kuru göz hastalığı göz yaşı içeriğini ve oküler yüzeyi etkileyen bir hastalıktır. Kornea epitel defektinden kornea delinmesine uzanan çeşitli oküler bulgular bu hastalıkla ilişkilidir (1). Kuru göz hastalığı en sık görülen göz hastalıklarından biridir. Yapılan toplum temelli prevalans çalışmalarında oranlar farklılık göstermekte olup %5 ile %35 arasında değişmektedir (2). Hastalık kadın cinsiyet, yaşlılar ve Asya ırkına mensup bireylerde daha sık gözlenmektedir (3-5). Etyopatogenezinde; hormonal değişimler, sigara kullanımı, oküler cerrahi, ilaç kullanımı, allerjenler, düşük nem düzeyi, yüksek oda sıcaklığı ve kontakt lens kullanımının rol oynadığı bildirilmiştir (5). Hastalıkla ilişkili oküler rahatsızlık, yabancı cisim hissi ve ağrı semptomlarının bireyin yaşam kalitesini olumsuz olarak etkilediği ve ruh sağlığı ile ilgili problemleri beraberinde getirdiği Ya z›fl ma Ad re si/Ad dress for Cor res pon den ce:
Kleptomania as a type of impulse control disorder (ICD) characterized by an inability to resist urges to steal objects not valuable or needed for personal use. Kleptomania may co-occurs with many psychiatric disorders frequently other impulse control disorders, obsessive-compulsive disorder, anxiety disorders, affective disorders, eating disorders and substance use disorders. We presented two adolescent cases admitted to Marmara University Child and Adolescent Psychiatry outpatient clinic because of stealing behavior and diagnosed with Kleptomania and ADHD. Both cases had improvement in stealing behavior after ADHD treatment.Careful monitoring of comorbid conditions in the psychiatric evaluation of Kleptomania cases is very important in terms of treatment and prognosis.
Objectives: Schizophrenia is a disorder with different clinical features. Schizophrenia may start insidiously and slow and go on for many years. But the negative symptoms and deficiency symptoms leading to social deterioration may come to the forefront. All these factors are taken into consideration, our aim in this study was to examine the demographic and clinical effects of symptoms on schizophrenic patients who have not yet been treated. Methods: Eighty patients who were admitted to the Ankara Numune Training and Research Hospital Psychiatry Outpatient Clinic, who did not have any previous antipsychotic medications and who did not use medications at the time of admission and who met the criteria for schizophrenia according to the DSM-5. Sociodemografic Data Form and the PANSS scale were used to assess the clinical status of the patients. Results: When the demographic characteristics of the participants were examined, 33 (41.2%) were female and 47 (58.8%) were male. The mean age of the patients was 31.08±9.37; mean education year was 8.76±3.53. When the patients participating in the study were evaluated in terms of gender, marital status, working status, smoking status, and family history, no statistical differences were found between the groups in terms of their PANSS scores (p>0.05). However, the PANSS Negative subscale scores (p<.001), general psychopathology scores (p=0.006), and total PANSS scores (p=0.003) were statistically significantly different between the three groups when the patients were untreated for 0-1 years, 1-5 years, and 5 years. Conclusions: In this study none of the sociodemographic factors we assessed had any effect on symptom severity. However, there are different results in the literature regarding gender, age, marital status and working status. Besides, it has been determined that the most important clinical manifestation in our study is the period without treatment. Further studies should identify demographic and clinical features that affect schizophrenic symptom changes.
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