Background: Fluid and electrolyte derangement are the immediate causes that increases the mortality in diarrhea. The present study was carried out among children of 4 months to 5 years with dehydration due to acute diarrhea to determine the serum electrolyte profile.
Methods: A hospital based cross sectional study was carried out in department of pediatrics, RIMS during a period of two years (sept 2019-Aug 2021).
Results: A total of 195 patients of 4 months to 5 years of age group presented with acute gastroenteritis were included in the study, among them hyponatreamia was the most frequent electrolyte abnormality noted (37.4%). Most (65.5%) of hyponatremic patients in our study took dilute ORS whereas majority (64.2%) of patients who took appropriate ORS had normal serum sodium levels. Frequency and duration of diarrhea, dehydration status and inappropriate ORS were significant risk factors for serum electrolyte and acid base imbalances.
Conclusions: Electrolyte abnormalities were significantly associated with frequency and duration of diarrhea, dehydration status and inappropriate ORS administration. Hence, timely recognition and management of electrolyte abnormalities and appropriate ORS administration improves outcome in acute gastroenteritis related dehydration in children.
Background: Neonatal hyperbilirubinemia, defined as a total serum bilirubin level above 5 mg/dl (86 μmol/l). Haemolytic disease of the newborn due to blood group incompatibilities between mother and foetus is one of the commonest cause of hyperbilirubinemia in the newborn.
Methods: A Hospital based cross sectional study was conducted among newborns admitted with jaundice.
Results: In our study 51 cases of neonatal jaundice were due to ABO incompatibility and among them 24 were having O-A incompatibility and 27 were having O-B incompatibility. The mean serum bilirubin in patients with ABO incompatibility were higher (24.8) than those without ABO incompatibility.
Conclusions: In the present study, one third of newborns with neonatal jaundice were having ABO incompatibility. The mean serum bilirubin in patients with ABO incompatibility were higher than those without ABO incompatibility. This highlights the importance of recognizing ABO Rh incompatibility in neonatal jaundice.
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