<p>Objetivo: evaluar los efectos de un programa estructurado de educación en prediabetes (pre-d) y Diabetes Mellitus tipo 2 (dm2), impartido en el primer nivel de atención. Métodos: estudio cuasiexperimental, antes-después, en 98 pacientes de ambos sexos sin seguridad social, de 20 años de edad o más, con diagnóstico de pre-d o dm2. Se evaluaron hemoglobina glucosilada (HbA1c), peso corporal e imc de manera previa y posterior a las 12 sesiones educativas. Se utilizó prueba t-Student para muestras dependientes. Resultados: el grupo de pre-d estuvo conformado por 27 pacientes y el de dm2 por 71 pacientes. Después del programa educativo, la HbA1c disminuyó 0.30% (p=0.073) en los pacientes con pre-d, y 1.05% (p=0.000) en aquellos con dm2; el primer grupo bajó en peso corporal 870 g (p=0.010) y en el segundo, 820 g (p=0.016). Conclusiones: la educación en pre-d y dm2 puede promover cambios positivos en el autocuidado y tratamiento médico del paciente.</p>
Introduction: New metabolomic biomarkers as Quantose™ IR and anthropometric measurements using bioelectrical impedance analysis (BIA) provide relevant information on patients with insulin resistance and prediabetes. QuantoseTM IR is a novel metabolomic test to assess insulin resistance for screening and monitoring. Establishing a correlation between these variables is useful in clinical practice and, to our knowledge, there are no published studies that explore the relationship between Quantose™ IR and anthropometric measurements using BIA in patients with prediabetes. Objective: To evaluate the correlation between Quantose™ IR and BIA anthropometric variables (fat mass, FM; fat mass index, FMI; and body mass index, BMI) in Mexican patients with prediabetes, overweight, and obesity. Materials and Methods: This is an observational, transversal analytic study in 135 patients of both genders between 20 and 65 years of age, BMI 25.0–34.9, with diagnosis of prediabetes. The Quantose™ IR test was performed as well as anthropometric measurements (FM, FMI, and BMI) using BIA taken with Inbody 230TM. Pearson’s correlations and independent sample t-tests were estimated with a significance level of p < 0.05. Results: 135 patients were studied; 77% were female, aged 46 years in average. The prevalence of insulin resistance by Quantose™ IR was 71.1%. A positive correlation was confirmed between Quantose™ IR and FM, FMI, and BMI (p < 0.05). Patients with altered Quantose™ IR had higher FM, FMI, and BMI (p < 0.05). Conclusion: The data here presented confirm the existence of a positive and statistically significant correlation between Quantose™ IR and anthropometric measurements using BIA. This information may be useful for diagnosis and treatment in prediabetic, overweight, and obese patients.
La presencia de sobrepeso u obesidad es uno de los factores de riesgo modificables más importantes asociados con prediabetes y diabetes tipo 2 en todos los grupos de edad. En la actualidad, uno de cada tres niños y adolescentes mexicanos entre los seis y 19 años padece sobrepeso u obesidad. Los programas en el estilo de vida son prioritarios para impulsar el mantenimiento de un peso saludable y prevenir prediabetes y diabetes tipo 2. Objetivo: Evaluar el efecto de una intervención educativa en el estilo de vida para prevenir prediabetes o diabetes tipo 2 en niños mexicanos. Material y métodos: Piloto de un ensayo clínico controlado aleatorizado,
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