Liquid smoke made from green betel leaf (Piper betle L) and red betel leaf (Piper crocatum Ruiz & Pav) has been made by pyrolysis. To determine the allegations of the chemical compounds contained in these two liquid smoke, they were tested by Gas Chromatography-Mass Spectrometry (GC-MS) method. Based on the test results it was found that there were 7 suspected compounds in the liquid smoke of green betel leaf and 30 compounds in red betel liquid smoke. The main compounds contained in the liquid smoke of green betel leaf are Isamoxole as the anti-allergic, 5,10-Diethoxy-2,3,7,8-tetrahydro-1H, 6H-dipyrrolo [1,2-a; 1', 2'-d ] Pyrazine as an antifungal and 3,5-Dimethoxyphenol has the potential to be antibacterial while in red betel leaves are 4-(1H-1,3-Benzodiazol-2-yl) phenol and Benzene, 1,2,3trimethoxy-5-(2 -propenyl) -Bioactivity potential of the two compounds has not been found. KARAKTERISASI KIMIA ASAP CAIR HASIL PIROLISIS DAUN SIRIH HIJAU (Piper betle L) DAN MERAH (Piper crocatum Ruiz&Pav) ABSTRAKAsap cair berbahan baku daun sirih hijau (Piper betle L) dan daun sirih merah (Piper crocatum Ruiz& Pav) telah dibuat dengan cara pirolisis. Untuk mengetahui dugaan senyawa kimia yang terkandung dalam kedua asap cair ini, produk asap cair diuji dengan metode KromatografiGas-Spektroskopi Massa (KG-SM). Berdasarkan hasil pengujian ditemukan terdapat 7 dugaan senyawa dalam asap cair daun sirih hijau dan 30 senyawa dalam asap cair sirih merah. Senyawa utama yang terdapat dalam asap cair daun sirih hijau adalah Isamoxolesebagai antialergi berikutnya 5, 3,7,6Hdipyrrolo[1,1',pyrazine sebagai antijamur dan 3,5-Dimethoxyphenol berpotensi sebagai antibakteri sedangkan dalam daun sirih merah yaitu 4-(1H-1,3-Benzodiazol-2-yl)phenol dan Benzene, 1,2,3-trimethoxy-5-(2-propenyl)-belum ditemukan potensi bioaktivitas dari kedua senyawa tersebut. Kata Kunci :Asap Cair, Piper betle L, Piper crocatum Ruiz& Pav SANITAS: JURNAL TEKNOLOGI DAN SENI KESEHATAN
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