Oral carcinogenesis is known as multifactorial process which engaged plentiful genetic events that transform normal activity of tumor suppressor genes and oncogenes. It is observed that aggregation of genetic alterations is the ground for advancement of a normal cell to cancer cells, which is known as a multi-step carcinogenesis. Because of this event, growth factor production increases as well as increase in total of receptors on cell surface and increased intracellular signal messengers. The present review scrutinize the existing documentation in the literature related to the oral squamous cell carcinoma. English language articles were searched in various databases such as Pubmed, Scopus, Science direct and Google scholar. The keyword used for searching are “oral squamous cell carcinoma”, “Genetics and Oral squamous cell carcinoma”,“Molecular mechanism in oral squamous cell carcinoma”. The present review spotlights on understanding the molecular mechanism and the genetic factors which is responsible for alteration in the cell which leads to oral squamous cell carcinoma.
Important dietary components known as nutraceuticals have both therapeutic and nutritional impacts. The active ingredients in these foods, including such carotenoids, collagen hydrolysate, and dietary fibers, are what provide them their health benefits. Nutraceuticals have been shown to have a good impact on immunological and cardiovascular health, as well as play a part in the prevention of infections and cancer. Depending on its nature and manner of action, nutraceuticals can be divided into many types. Various nutraceutical categories and their therapeutic potential effects, including anti-cancer, antioxidant, anti-inflammatory, and anti-lipid activity in disease, will be examined in this study. In addition, the many ways in which these accepted methods and structures, their application, and human safety would be covered, along with recent trends and nutraceuticals’ potential for the development.
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