No abstract

No abstract

No abstract

No abstract

The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summarize recent research progress in the area, which may be conducive to the development of Wnt-based therapeutic strategies for bone repair. [BMB Reports 2014; 47(12): 666-672]

No abstract

Based on the linear potential flow theory and matching eigen-function expansion technique, an analytical model is developed to investigate the hydrodynamics of two-dimensional dual-pontoon floating breakwaters that also work as oscillating buoy wave energy converters (referred to as the integrated system hereafter). The pontoons are constrained to heave motion independently and the linear power take-off damping is used to calculate the absorbed power. The proposed model is verified by using the energy conservation principle. The effects of the geometrical parameters on the hydrodynamic properties of the integrated system, including the reflection and transmission coefficients and CWR (capture width ratio, which is defined as the ratio of absorbed wave power to the incident wave power in the device width). It is found that the natural frequency of the heave motion and the spacing of the two pontoons are the critical factors affecting the performance of the integrated system. The comparison between the results of the dual-pontoon breakwater and those of the single-pontoon breakwater shows that the effective frequency range (for condition of transmission coefficient K T < 0.5 and the total capture width ratio η total > 20%) of the dual-pontoon system is broader than that of the single-pontoon system with the same total volume.

No abstract