In the mesopic range, mild hypoxia impairs chromatic sensitivity progressively with reducing luminance. Binocular summation of chromatic signals is consistent and independent of the luminance channel. The CAD test is highly sensitive to mild congenital and acquired color vision deficiencies.
Mild hypoxia degrades low contrast acuity progressively with decreasing mesopic luminance. At 0.1 cd x m(-2), supplementary oxygen enhances low contrast acuity, implying that visual performance is oxygen-dependent in the mid-mesopic range. Relative to performance under mild hypoxia at 3048 m (10,000 ft), supplementary oxygen can extend functionally useful vision to lower light levels. The findings are relevant to contemporary military night flying, viewing the external scene directly or through night vision devices, or viewing dimly illuminated flight deck instruments.
This study examined the time course of early scotopic threshold sensitivity during dark adaptation under mild to moderate hypoxia, moderate hypocapnia and hyperoxia, measuring detection time displacement relative to normoxia. Cone rod inflection and early rod adaptation were highlighted using progressively dimmer green flash stimuli. Early scotopic sensitivity was significantly delayed by hypoxia and hastened by hypocapnia and hyperoxia. Effects of respiratory disturbance on dark adaptation include temporal shifts of early scotopic sensitivity while human rod photoreceptors appear functionally hypoxic when breathing air at one atmosphere. At night, supplementary oxygen may benefit aircrew visual sensitivity, even at ground level.
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