Introduction: The use of local natural products, such as honey, is empirically prescribed in the treatment of burns and several medical conditions. Aim: This was conducted to evaluate the burn wound healing activity of three types of local types of honey on rats. Materials and Methods: This was a comparative experimental study held at the Faculty of Medicine and Biomedical Sciences of the University of Yaoundé I. We used 3 varieties of honey designated by their cities of origin: Ngaoundal, Okuh, and Yaounde. Brulex® (Zinc Oxide) was our reference medicine against burns. Male rats of the Wistar strain have served as animal material on which the burns were performed. There were 36 individuals divided into 4 groups of 9 rats per batch for treatment with reference medicine and 3 honey samples. We realized experimental burns under general anesthesia by a heated mass. The surface areas were calculated using Autodesk AutoCAD 2014® software. The photos were taken using an XTIGI V10® telephone. At the various dates selected, the wound surfaces calculated for each batch were expressed in the form of the mean ± standard deviation. Results: There wa no significant variation in pH and free acidity. Okuh honey is the most acidic (pH 5.73 ± 0.682). Concerning the Brix degree, the least sweet honey is that of Okuh (73.94 ± 0.115). There is a significant difference in the Brix degree between these three samples (p=0.00000009; Table 1). The richest honey in metabolites was that of Ngaoundal, with polyphenols of 323.79±53.57 mEq/kg, flavonoids of 47.45±3.84 mEq/kg and total flavonols of 21 .82±0.90 mEq/kg. Concerning the evolution of the healing process, the group of rats treated with Brulex® showed the largest injured surfaces on day 0 (8.83 ± 2.34 cm2), the least extensive being those of the Okuh group (6.83 ± 0.66 cm2). On the 24th day, the smallest areas were in order those of the Ngaoundal, Yaounde, and Okuh lots. While the rats in the Brulex® and negative control lots were not yet completely cured. On histology sections, Okuh, Yaoundé, and Ngaoundal groups had slight fibrosis, hypervascularization and an abundance of immune cells. Conclusion: The three honey type seem effective in burn wound care and can be suggested.
Backgroung: the infraorbital foramen (IOF) is a hole located in the maxillary bone and delivering passage to the infra orbital vascular-nervous bundle. It is an essential structure in the management of orofacial pathologies. Its precise location allows optimal anesthesia of the infraorbital nerve during cleft lip and palate surgery or alcoholization during the management of essential V2 neuralgia. The aim of our research was to determine the morphology and morphometry of the infraorbital foramen in a sample of the Cameroonian population. Methods: we included 208 CT-Scans of patients meeting our search criteria. We determined the shape of the IOF and evaluated the transverse and vertical diameters of the IOF. We assessed the distance of the IOF from the maxillary alveolar crest, the lateral border of the piriform aperture and the infraorbital margin. The Student test was used to determine the association between different variables. the P-value of 0.05 was considered significant and the confidence interval was 95%. Results: The mean transverse diameter of the left IOF was 1.97 mm ± 0.51 while 1.78 mm ± 0.53. The IOF was more often medial to the lateral palpebral commissure- nasal wing line on the left and right (78.8% and 72.6%, respectively). Our sample showed that in 35.6% (n=94) of subjects, the IOF was round on the left, whereas it was round in 45.2% (n=94) of patients. Conclusion: the position of the IOF is of particular interest in the management of facial pathologies. Knowing its location makes it possible to avoid a section of the infraorbital neurovascular bundle that can cause sometimes irreversible sequelae.
Introduction the infraorbital foramen (IOF) is a hole located in the maxillary bone and delivering passage to the infra orbital vascular-nervous bundle. It is an essential structure in the management of orofacial pathologies. Its precise location allows optimal anesthesia of the infraorbital nerve during cleft lip and palate surgery or alcoholization during the management of essential V2 neuralgia. The aim of our research was to determine the morphology and morphometry of the infraorbital foramen in a sample of the Cameroonian population. Methods we included 208 CT-scans of patients meeting our search criteria. We determined the shape of the IOF and evaluated the transverse and vertical diameters of the IOF. We assessed the distance of the IOF from the maxillary alveolar crest and the infraorbital margin. The Student test was used to determine the association between different variables. The P-value of 0.05 was considered significant and the confidence interval was 95%. Results male subjects represented 52.4% (n=109) of our participants and the mean age of our population was 26 years ± 7.3. The mean transverse diameter of the left IOF was 1.97 mm ± 0.51 while 1.78 mm ± 0.53. The IOF was more often medial to the lateral palpebral commissure-nasal wing line on the left and right (78.8% and 72.6%, respectively). Our sample showed that in 54.6% (n=113) of subjects, the IOF was oval on the left side, whereas on the right side, the IOF was oval in 52.3% (n=109) of patients. Conclusion our study showed that to locate the IOF in a Cameroonian individual, one must palpate the vestibular mucosa opposite the maxillary first molar. Then, one must follow the line passing over this tooth, the IOF is located at about 7 mm from the infra-orbital border and 16 mm from the lateral nasal wall. We have shown that the IOF is located medial to the line connecting the nasal wing to the external palpebral commissure.
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