Periodontitis, being one of the most frequent oral diseases, has remarkably high prevalence and is considered as an extensive public health problem. 1 It is a multifactorial chronic infectious disease, which might cause loss of periodontal ligament, alveolar bone and even the affected tooth. 2 It is closely related to symptoms including gingival bleeding, gingival recession, sensitivity, halitosis and is also potentially associated with 57 different systemic diseases and conditions. 3 It has been suggested that periodontitis may lead to pain and