We introduce SOCIAL IQA, the first largescale benchmark for commonsense reasoning about social situations. SOCIAL IQA contains 38,000 multiple choice questions for probing emotional and social intelligence in a variety of everyday situations (e.g., Q: "Jordan wanted to tell Tracy a secret, so Jordan leaned towards Tracy. Why did Jordan do this?" A: "Make sure no one else could hear"). Through crowdsourcing, we collect commonsense questions along with correct and incorrect answers about social interactions, using a new framework that mitigates stylistic artifacts in incorrect answers by asking workers to provide the right answer to a different but related question. Empirical results show that our benchmark is challenging for existing question-answering models based on pretrained language models, compared to human performance (>20% gap). Notably, we further establish SOCIAL IQA as a resource for transfer learning of commonsense knowledge, achieving state-of-the-art performance on multiple commonsense reasoning tasks (Winograd Schemas, COPA).

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We consider negotiation settings in which two agents use natural language to bargain on goods. Agents need to decide on both high-level strategy (e.g., proposing $50) and the execution of that strategy (e.g., generating "The bike is brand new. Selling for just $50!"). Recent work on negotiation trains neural models, but their end-to-end nature makes it hard to control their strategy, and reinforcement learning tends to lead to degenerate solutions. In this paper, we propose a modular approach based on coarse dialogue acts (e.g., propose(price=50)) that decouples strategy and generation. We show that we can flexibly set the strategy using supervised learning, reinforcement learning, or domain-specific knowledge without degeneracy, while our retrieval-based generation can maintain context-awareness and produce diverse utterances. We test our approach on the recently proposed DEALORNODEAL game, and we also collect a richer dataset based on real items on Craigslist. Human evaluation shows that our systems achieve higher task success rate and more human-like negotiation behavior than previous approaches.

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Existing goal-oriented dialogue datasets focus mainly on identifying slots and values. However, customer support interactions in reality often involve agents following multi-step procedures derived from explicitly-defined company policies as well. To study customer service dialogue systems in more realistic settings, we introduce the Action-Based Conversations Dataset (ABCD), a fully-labeled dataset with over 10K human-to-human dialogues containing 55 distinct user intents requiring unique sequences of actions constrained by policies to achieve task success.We propose two additional dialog tasks, Action State Tracking and Cascading Dialogue Success, and establish a series of baselines involving large-scale, pre-trained language models on this dataset. Empirical results demonstrate that while more sophisticated networks outperform simpler models, a considerable gap (50.8% absolute accuracy) still exists to reach human-level performance on ABCD. 1

Existing goal-oriented dialogue datasets focus mainly on identifying slots and values. However, customer support interactions in reality often involve agents following multi-step procedures derived from explicitly-defined company policies as well. To study customer service dialogue systems in more realistic settings, we introduce the Action-Based Conversations Dataset (ABCD), a fully-labeled dataset with over 10K human-to-human dialogues containing 55 distinct user intents requiring unique sequences of actions constrained by policies to achieve task success.We propose two additional dialog tasks, Action State Tracking and Cascading Dialogue Success, and establish a series of baselines involving large-scale, pre-trained language models on this dataset. Empirical results demonstrate that while more sophisticated networks outperform simpler models, a considerable gap (50.8% absolute accuracy) still exists to reach human-level performance on ABCD. 1

Triple negative breast cancer (TNBC) is a particularly aggressive cancer subtype that is difficult to diagnose due to its discriminating epidemiology and obscure metabolome. For the first time, 3D spatial and chemometric analyses uncover the unique lipid metabolome of TNBC under the tandem modulation of two key metabolites – insulin and methionine - using non-invasive optical techniques. By conjugating heavy water (D2O) probed Raman scattering with label-free two-photon fluorescence (TPF) microscopy, we observed altered de novo lipogenesis, 3D lipid droplet morphology, and lipid peroxidation under various methionine and insulin concentrations. Quantitative interrogation of both spatial and chemometric lipid metabolism under tandem metabolite modulation confirms significant interaction of insulin and methionine, which may prove to be critical therapeutic targets, and proposes a powerful optical imaging platform with subcellular resolution for metabolic and cancer research.

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